Kidney extracellular matrix hydrogel enhances therapeutic potential of adipose-derived mesenchymal stem cells for renal ischemia reperfusion injury

C Zhou, L Zhou, J Liu, L Xu, Z Xu, Z Chen, Y Ge… - Acta biomaterialia, 2020 - Elsevier
Stem cell-based therapy has been suggested as a promising option for the treatment of
renal ischemia-reperfusion injury (IRI). However, how to efficiently deliver stem cells remains …

The use of chitosan based hydrogel for enhancing the therapeutic benefits of adipose-derived MSCs for acute kidney injury

J Gao, R Liu, J Wu, Z Liu, J Li, J Zhou, T Hao, Y Wang… - Biomaterials, 2012 - Elsevier
Transplantation of mesenchymal stem cells (MSCs) has been reported a great therapeutic
potential for acute kidney injury (AKI). However, the therapeutic benefits are limited due to …

Regenerative abilities of mesenchymal stem cells via acting as an ideal vehicle for subcellular component delivery in acute kidney injury

L Zhao, C Hu, F Han, J Wang… - Journal of cellular and …, 2020 - Wiley Online Library
Cell‐to‐cell communication and information exchange is one of the most important events in
multiple physiological processes, including multicellular organism development, cellular …

Comparison of human adipose stromal vascular fraction and adipose-derived mesenchymal stem cells for the attenuation of acute renal ischemia/reperfusion injury

L Zhou, Q Song, J Shen, L Xu, Z Xu, R Wu, Y Ge… - Scientific reports, 2017 - nature.com
Stem cells therapy has been suggested as a promising option for the treatment of acute
kidney injury (AKI). This study was performed to compare the abilities of xenogenic …

Adipose‐derived mesenchymal stem cells therapy for acute kidney injury induced by ischemia‐reperfusion in a rat model

JB Zhang, XQ Wang, GL Lu… - Clinical and …, 2017 - Wiley Online Library
Acute kidney injury (AKI) represents a group of complicated syndromes with a high mortality
rate. The administration of adipose‐derived mesenchymal stem cells (ADMSC s) has been …

Not a process of simple vicariousness, the differentiation of human adipose-derived mesenchymal stem cells to renal tubular epithelial cells plays an important role in …

K Li, Q Han, X Yan, L Liao, RC Zhao - Stem cells and development, 2010 - liebertpub.com
The recent findings indicate that under conditions of severe tubular injuries, transplantation
of mesenchymal stem cells (MSCs) may be a promising treatment in acute kidney diseases; …

[HTML][HTML] Three-dimensional aggregates enhance the therapeutic effects of adipose mesenchymal stem cells for ischemia-reperfusion induced kidney injury in rats

X Zhao, X Qiu, Y Zhang, S Zhang, X Gu… - Stem cells …, 2016 - hindawi.com
It has been shown that administration of adipose derived mesenchymal stem cells
(AdMSCs) enhanced structural and functional recovery of renal ischemia-reperfusion (IR) …

Comparison of the treatment efficacy of umbilical mesenchymal stem cell transplantation via renal subcapsular and parenchymal routes in AKI-CKD mice

M Huang, D Li, J Chen, Y Ji, T Su, Y Chen… - Stem cell research & …, 2022 - Springer
Abstract Background Mesenchymal stem cells (MSCs) have emerged as a promising cell-
based therapy for acute kidney injury (AKI). However, the optimal route of MSC …

Hypoxic mesenchymal stem cells ameliorate acute kidney ischemia-reperfusion injury via enhancing renal tubular autophagy

WC Tseng, PY Lee, MT Tsai, FP Chang… - Stem Cell Research & …, 2021 - Springer
Background Acute kidney injury (AKI) is an emerging global healthcare issue without
effective therapy yet. Autophagy recycles damaged organelles and helps maintain tissue …

Integrin receptor-binding nanofibrous peptide hydrogel for combined mesenchymal stem cell therapy and nitric oxide delivery in renal ischemia/reperfusion injury

H Najafi, SS Abolmaali, R Heidari, H Valizadeh… - Stem Cell Research & …, 2022 - Springer
Background Mesenchymal-based therapy has been utilized as a practical approach in the
treatment of renal ischemia/reperfusion (I/R) injury. However, low cell retention and survival …