Combination of adipose-derived mesenchymal stem cells (ADMSC) and ADMSC-derived exosomes for protecting kidney from acute ischemia–reperfusion injury

KC Lin, HK Yip, PL Shao, SC Wu, KH Chen… - International journal of …, 2016 - Elsevier
Background In this study, we tested the hypothesis that a combined adipose-derived
mesenchymal stem cell (ADMSC) and ADMSC-derived exosome therapy protected rat …

[HTML][HTML] Maximum efficacy of mesenchymal stem cells in rat model of renal ischemia-reperfusion injury: renal artery administration with optimal numbers

J Cai, X Yu, R Xu, Y Fang, X Qian, S Liu, J Teng… - PloS one, 2014 - journals.plos.org
Backgrounds Despite the potential therapeutic benefits, cell therapy in renal ischemia-
reperfusion (I/R) injury is currently limited by low rates of cell engraftment after systemic …

[HTML][HTML] Potential advantages of acute kidney injury management by mesenchymal stem cells

F Bianchi, E Sala, C Donadei, I Capelli… - World Journal of Stem …, 2014 - ncbi.nlm.nih.gov
Mesenchymal stem cells are currently considered as a promising tool for therapeutic
application in acute kidney injury (AKI) management. AKI is characterized by acute tubular …

Possible mechanisms for the renoprotective action of adipose-derived mesenchymal stem cells with CD44-targeted hyaluronic acid against renal ischemia

A Awadalla, AM Hussein, M Ali, N Barakat, ET Hamam… - Life Sciences, 2021 - Elsevier
The present study aimed to investigate the invitro preconditioning of adipose-derived
mesenchymal stem cells (ADMSCs) with CD44-targeted hyalournic acid (HA) on ischemic …

Human decellularized adipose matrix derived hydrogel assists mesenchymal stem cells delivery and accelerates chronic wound healing

Z Chen, B Zhang, J Shu, H Wang, Y Han… - … Research Part A, 2021 - Wiley Online Library
Biological scaffolds based stem cell delivery methods have emerged as a promising
approach for tissue repair and regeneration. Here we developed a hydrogel biological …

Mesenchymal stem cells: a promising therapeutic tool for acute kidney injury

RE Selim, HH Ahmed, SH Abd-Allah, GM Sabry… - Applied biochemistry …, 2019 - Springer
Acute kidney injury (AKI) is a rapid loss of renal function. It has high mortality rates. Still,
renal replacement therapy is considered the best solution for recovering AKI. This opens a …

[HTML][HTML] Molecular mechanisms of mesenchymal stem cell-based therapy in acute kidney injury

PW Lee, BS Wu, CY Yang, OKS Lee - International journal of molecular …, 2021 - mdpi.com
Acute kidney injury (AKI) causes a lot of harm to human health but is treated by only
supportive therapy in most cases. Recent evidence shows that mesenchymal stem cells …

Nestin+ kidney resident mesenchymal stem cells for the treatment of acute kidney ischemia injury

MH Jiang, G Li, J Liu, L Liu, B Wu, W Huang, W He… - Biomaterials, 2015 - Elsevier
Renal resident mesenchymal stem cells (MSCs) are important regulators of kidney
homeostasis, repair or regeneration. However, natural distribution and the starting …

[HTML][HTML] Cyclosporine-assisted adipose-derived mesenchymal stem cell therapy to mitigate acute kidney ischemia–reperfusion injury

YT Chen, CC Yang, YY Zhen, CG Wallace… - Stem cell research & …, 2013 - Springer
Introduction This study tested the hypothesis that cyclosporine (CsA)-supported syngeneic
adipose-derived mesenchymal stem cell (ADMSC) therapy offered superior attenuation of …

Artificial kidney capsule packed with mesenchymal stem cell-laden hydrogel for the treatment of rhabdomyolysis-induced acute kidney injury

Z Fu, Y Chu, X Geng, Y Ma, K Chi, C Song… - ACS Biomaterials …, 2022 - ACS Publications
Acute kidney injury (AKI) has emerged as a major public health problem affecting millions of
people worldwide without specific and satisfactory therapies due to the lack of an effective …