Acute kidney injury (AKI) is a complex clinical condition associated with significant morbidity
and mortality and lacking effective management. Ischemia‑reperfusion injury (IRI) remains …

Background: Acute kidney injury is a major challenge in critical care medicine, with high
rates of in-hospital morbidity and mortality. Stem cell therapy has emerged as an evolving …

Acute kidney injury (AKI) is a frequent clinical disease with a high morbidity rate and
mortality rate, while the treatment options for this intractable disease are limited currently. In …

Ischemia/reperfusion (I/R) injury is an inevitable consequence of organ transplantation and
a major determinant of patient and graft survival in kidney transplantation. Renal I/R injury …

Hypoxia preconditioning has been confirmed as an effective strategy to enhance the
therapeutic potentials of mesenchymal stem cells (MSCs), such as for myocardial ischemia …

Kidney disease (KD) is a life-threatening disease characterized by high morbidity and
mortality in clinical settings, which can be caused by many reasons, and the incidence …

Background: Three-dimensional (3D) culture has been reported to increase the therapeutic
potential of mesenchymal stem cells (MSCs). The present study assessed the therapeutic …

Human umbilical cord–derived mesenchymal stem cells (hucMSCs) are particularly
attractive cells for cellular and gene therapy in acute kidney injury (AKI). Adenovirus …

Ischemia-reperfusion injury (IRI) is a major cause of acute kidney injury, which is a serious
clinical condition with no effective pharmacological treatment. Mesenchymal stem cell …

Mesenchymal stem cell (MSC) transplantation is a promising therapy for acute kidney injury;
however, the efficacy is limited due to poor survival after transplantation. In this study, we …