Renal fibrosis is one of the largest global health care problems, and microvascular (MV)
injury is important in the development of progressive fibrosis. Although conventional cell …

Background. Acute kidney injury (AKI) represents a major clinical problem with high mortality
and limited causal treatments. The use of cell therapy has been suggested as a potential …

Background Renal fibrosis is a common pathological process of chronic kidney diseases
induced by multiple factors. Hypoxic pretreatment of mesenchymal stem cells can enhance …

Hydrogels, highly‐hydrated crosslinked polymer networks, closely mimic the
microenvironment of native extracellular matrix (ECM) and thus present as ideal platforms …

Administration of fibroblastic cells derived from a number of tissues (collectively called
“mesenchymal stem cells”) has been suggested to be beneficial for renal repair and …

Aims Naturally secreted extracellular vesicles (EVs) play important roles in stem-mediated
cardioprotection. This study aimed to investigate the cardioprotective function and …

Mesenchymal stem cells (MSCs) have emerged as ideal cell-based therapeutic candidates
for the structural and functional restoration of the diseased kidney. Glial cell line-derived …

Renal ischemia/reperfusion (I/R) injury is the main reason for acute kidney injury (AKI) and is
closely related to high morbidity and mortality. In this study, we found that exosomes from …

BACKGROUND: Ischemia followed by reperfusion leads to acute renal failure in both native
kidneys and a renal allograft. Our previous study found that transplantation of mesenchymal …

Background Poor cell engraftment and survival after transplantation limited the application of
stem cell therapy. Synthetic biomaterials could provide an artificial microenvironment for …