Coordination of mitotic exit with chromosome segregation is key for successful mitosis.
Mitotic exit in budding yeast is executed by the mitotic exit network (MEN), which is …

The spatiotemporal control of mitotic exit is crucial for faithful chromosome segregation
during mitosis. In budding yeast, the mitotic exit network (MEN) drives cells out of mitosis …

In budding yeast, a surveillance mechanism known as the spindle position checkpoint
(SPOC) ensures accurate genome partitioning. In the event of spindle misposition, the …

The spindle position checkpoint (SPOC) is a mitotic surveillance mechanism in
Saccharomyces cerevisiae that prevents cells from completing mitosis in response to …

Spindle checkpoint silencing is a critical step during mitosis that initiates chromosome
segregation, yet surprisingly little is known about its mechanism. Protein phosphatase I …

Accurate nuclear position is essential for each daughter cell to receive one DNA
complement. In budding yeast, a surveillance mechanism known as the spindle position …

Substrate dephosphorylation by the cyclin-dependent kinase (Cdk)-opposing phosphatase,
Cdc14, is vital for many events during budding yeast mitotic exit. Cdc14 is sequestered in …

In budding yeast, alignment of the anaphase spindle along the mother–bud axis is crucial for
maintaining genome integrity. If the anaphase spindle becomes misaligned in the mother …

Budding yeast asymmetric cell division relies upon the precise coordination of spindle
orientation and cell cycle progression. The spindle position checkpoint (SPOC) is a …

The spindle orientation checkpoint (SPOC) of budding yeast delays mitotic exit when
cytoplasmic microtubules (MTs) are defective, causing the spindle to become misaligned …