Transcriptome profiling of antimicrobial resistance in Pseudomonas aeruginosa
A Khaledi, M Schniederjans, S Pohl… - Antimicrobial agents …, 2016 - Am Soc Microbiol
Emerging resistance to antimicrobials and the lack of new antibiotic drug candidates
underscore the need for optimization of current diagnostics and therapies to diminish the …
underscore the need for optimization of current diagnostics and therapies to diminish the …
Predicting antimicrobial resistance in Pseudomonas aeruginosa with machine learning‐enabled molecular diagnostics
A Khaledi, A Weimann, M Schniederjans… - EMBO molecular …, 2020 - embopress.org
Limited therapy options due to antibiotic resistance underscore the need for optimization of
current diagnostics. In some bacterial species, antimicrobial resistance can be …
current diagnostics. In some bacterial species, antimicrobial resistance can be …
A large-scale whole-genome comparison shows that experimental evolution in response to antibiotics predicts changes in naturally evolved clinical Pseudomonas …
SJT Wardell, A Rehman, LW Martin… - Antimicrobial agents …, 2019 - Am Soc Microbiol
Pseudomonas aeruginosa is an opportunistic pathogen that causes a wide range of acute
and chronic infections. An increasing number of isolates have mutations that make them …
and chronic infections. An increasing number of isolates have mutations that make them …
[HTML][HTML] Virulence Characteristics and an Action Mode of Antibiotic Resistance in Multidrug-Resistant Pseudomonas aeruginosa
W Hwang, SS Yoon - Scientific reports, 2019 - nature.com
Pseudomonas aeruginosa displays intrinsic resistance to many antibiotics and known to
acquire actively genetic mutations for further resistance. In this study, we attempted to …
acquire actively genetic mutations for further resistance. In this study, we attempted to …
Comparative genomics of a drug-resistant Pseudomonas aeruginosa panel and the challenges of antimicrobial resistance prediction from genomes
J Jeukens, I Kukavica-Ibrulj… - FEMS microbiology …, 2017 - academic.oup.com
Antimicrobial resistance (AMR) is now recognized as a global threat to human health. The
accessibility of microbial whole-genome sequencing offers an invaluable opportunity for …
accessibility of microbial whole-genome sequencing offers an invaluable opportunity for …
[HTML][HTML] Genomic heterogeneity underlies multidrug resistance in Pseudomonas aeruginosa: A population-level analysis beyond susceptibility testing
LJ Rojas, M Yasmin, J Benjamino, SM Marshall… - PloS one, 2022 - journals.plos.org
Background Pseudomonas aeruginosa is a persistent and difficult-to-treat pathogen in many
patients, especially those with Cystic Fibrosis (CF). Herein, we describe a longitudinal …
patients, especially those with Cystic Fibrosis (CF). Herein, we describe a longitudinal …
[HTML][HTML] The Versatile Mutational Resistome of Pseudomonas aeruginosa
C López-Causapé, G Cabot… - Frontiers in …, 2018 - frontiersin.org
One of the most striking features of Pseudomonas aeruginosa is its outstanding capacity for
developing antimicrobial resistance to nearly all available antipseudomonal agents through …
developing antimicrobial resistance to nearly all available antipseudomonal agents through …
Antibiotic resistance in Pseudomonas aeruginosa and adaptation to complex dynamic environments
Antibiotic resistance has become a serious threat to human health (WHO Antibacterial
Agents in Clinical Development: an Analysis of the Antibacterial Clinical Development …
Agents in Clinical Development: an Analysis of the Antibacterial Clinical Development …
The resistome of Pseudomonas aeruginosa in relationship to phenotypic susceptibility
VN Kos, M Déraspe, RE McLaughlin… - Antimicrobial agents …, 2015 - Am Soc Microbiol
Many clinical isolates of Pseudomonas aeruginosa cause infections that are difficult to
eradicate due to their resistance to a wide variety of antibiotics. Key genetic determinants of …
eradicate due to their resistance to a wide variety of antibiotics. Key genetic determinants of …
Genomewide Identification of Genetic Determinants of Antimicrobial Drug Resistance in Pseudomonas aeruginosa
A Dötsch, T Becker, C Pommerenke… - Antimicrobial agents …, 2009 - Am Soc Microbiol
The emergence of antimicrobial drug resistance is of enormous public concern due to the
increased risk of delayed treatment of infections, the increased length of hospital stays, the …
increased risk of delayed treatment of infections, the increased length of hospital stays, the …
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