In this study, we investigated whether total saponin extract (TSE), ginsenoside Rb1, and Rb1
metabolite compound K, which are isolated from red ginseng, have antinociceptive effects …

Background Ginseng saponin has long been used as a traditional Asian medicine and is
known to be effective in treating various kinds of pain. Ginsenoside Rf is one of the …

Abstract Panax notoginseng (Chinese ginseng, Sanqi), one of the major ginseng species,
has been traditionally used to alleviate different types of chronic pain. The raw P …

The aim of this study was to investigate whether ginsenoside Rf can effectively relieve pain
hypersensitivity in a neuropathic pain rat model. Neuropathic pain was induced in rats by …

Several ginsenoside (R b1, R b2, R c, R d, R e, R f, R g1 and R g3) are neuroprotective and
antinociceptive agents. In this study, we assessed the effects of these ginsenosides …

Ginsenosides are main pharmacoactive molecules of ginseng. The antinociceptive activity of
ginsenosides after intrathecal (it) injection was examined in formalin test. We also …

Abstract Ginsenoside Rb1 (GRb1) is a major ingredient of ginseng, a traditional medicine
that has been used for thousands of years. Previous studies have reported that GRb1 had …

Aims The present study aims to evaluate the analgesic effect of ginsenoside Rg3 in different
mouse pain models. Main methods Formalin-, carrageenan-and S180 tumor cells induced …

The aim of this study was to assess the antinociceptive activity of ginseng total saponins
(GTS) on hyperalgesia induced by repeated intramuscular injections of acidic saline in rats …

Opioid-induced hyperalgesia (OIH) is characterized by nociceptive sensitization caused by
the cessation of chronic opioid use. OIH can limit the clinical use of opioid analgesics and …