Liposomes have been used as a drug delivery system in biological media. However, they
typically enter the cell via endocytic routes, which lower the delivery efficiency of the …

Liposomes represent important drug carrier vehicles in biological systems. A fusogenic
liposomal system composed of equimolar mixtures of the cationic lipid DOTAP and the …

Drug delivery systems based on liposome carriers that are designed for induction of
membrane fusion in response to the microenvironment have been investigated for more …

Lateral phase heterogeneity in biomembranes can govern cellular functions and may serve
as a platform for enrichment or depletion of membrane-anchored molecules. In this work, we …

Lipid-based nanoparticles, also called vesicles or liposomes, can be used as carriers for
drugs or many types of biological macromolecules, including DNA and proteins. Efficiency …

Cationic liposomes are frequently used as carrier particles for nucleic acid delivery. The
most popular formulation is the equimolar mixture of two components, a cationic lipid and a …

Current fusogenic liposomal delivery systems have limited applicability in vivo due to poor
stability in the blood and rapid clearance from the circulation. This is particularly true for …

Membrane fusion is a ubiquitous process in biology and is a prerequisite for many
intracellular delivery protocols relying on the use of liposomes as drug carriers. Here, we …

Introduction From viruses to organelles, fusion of biological membranes is used by diverse
biological systems to deliver macromolecules across membrane barriers. Membrane fusion …

As a novel fusogenic liposome, we designed liposomes modified with poly (glycidol) having
β-alanine residues, which is a poly (ethylene glycol) derivative with positively charged …