Cancer-testis antigens: Unique cancer stem cell biomarkers and targets for cancer therapy
O Gordeeva - Seminars in cancer biology, 2018 - Elsevier
Cancer-testis antigens (CTAs) are considered as unique and promising cancer biomarkers
and targets for cancer therapy. CTAs are multifunctional protein group with specific …
and targets for cancer therapy. CTAs are multifunctional protein group with specific …
Cancer/testis antigens: expression, regulation, tumor invasion, and use in immunotherapy of cancers
A Salmaninejad, MR Zamani… - Immunological …, 2016 - Taylor & Francis
Cancer/testis antigens (CTAs) are named based on their expression pattern that is restricted
in a number of normal and abnormal tissues. Tumor cells frequently express antigens whose …
in a number of normal and abnormal tissues. Tumor cells frequently express antigens whose …
[HTML][HTML] The expression, modulation and use of cancer-testis antigens as potential biomarkers for cancer immunotherapy
XF Li, P Ren, WZ Shen, X Jin… - American Journal of …, 2020 - ncbi.nlm.nih.gov
Cancer-testis antigens (CTA) are tumor antigens, present in the germ cells of testes, ovaries
and trophoblasts, which undergo deregulated expression in the tumor and malignant cells …
and trophoblasts, which undergo deregulated expression in the tumor and malignant cells …
Oncogenic cancer/testis antigens are a hallmarker of cancer and a sensible target for cancer immunotherapy
P Yang, M Meng, Q Zhou - Biochimica et Biophysica Acta (BBA)-Reviews …, 2021 - Elsevier
Increasing evidence shows that numerous cancer-testis antigens (CTAs) are uniquely
overexpressed in various types of cancer and most CTAs are oncogenic. Overexpression of …
overexpressed in various types of cancer and most CTAs are oncogenic. Overexpression of …
Tumor subtype-specific cancer–testis antigens as potential biomarkers and immunotherapeutic targets for cancers
J Yao, OL Caballero, WKA Yung, JN Weinstein… - Cancer immunology …, 2014 - AACR
Cancer–testis (CT) antigens are potential targets for cancer immunotherapy because of their
restricted expression in immune-privileged germ cells and various malignancies. Current …
restricted expression in immune-privileged germ cells and various malignancies. Current …
Cancer/testis antigens: from serology to mRNA cancer vaccine
Cancer/testis antigens (CTAs) are a group of tumor antigens expressed in numerous cancer
tissues, as well as in the testis and placental tissues. There are over 200 CTAs supported by …
tissues, as well as in the testis and placental tissues. There are over 200 CTAs supported by …
[HTML][HTML] Oncogenic cancer/testis antigens: prime candidates for immunotherapy
MF Gjerstorff, MH Andersen, HJ Ditzel - Oncotarget, 2015 - ncbi.nlm.nih.gov
Recent developments have set the stage for immunotherapy as a supplement to
conventional cancer treatment. Consequently, a significant effort is required to further …
conventional cancer treatment. Consequently, a significant effort is required to further …
Biology of cancer-testis antigens and their therapeutic implications in cancer
DS Nin, LW Deng - Cells, 2023 - mdpi.com
Tumour-specific antigens have been an area of interest in cancer therapy since their
discovery in the middle of the 20th century. In the era of immune-based cancer therapeutics …
discovery in the middle of the 20th century. In the era of immune-based cancer therapeutics …
Concise review: cancer/testis antigens, stem cells, and cancer
FF Costa, K Le Blanc, B Brodin - Stem cells, 2007 - academic.oup.com
In the multistep process of cancer development, the concept that cancer stem cells are
derived from normal stem cells that have gradually accumulated various genetic and …
derived from normal stem cells that have gradually accumulated various genetic and …
Cancer-testis antigens in ovarian cancer: implication for biomarkers and therapeutic targets
K Xie, C Fu, S Wang, H Xu, S Liu, Y Shao… - Journal of ovarian …, 2019 - Springer
Ovarian cancer remains the most fatal gynecologic malignancy worldwide due to delayed
diagnosis as well as recurrence and drug resistance. Thus, the development of new tumor …
diagnosis as well as recurrence and drug resistance. Thus, the development of new tumor …
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