TSNA exposure: levels of NNAL among Canadian tobacco users

CD Czoli, D Hammond - Nicotine & Tobacco Research, 2015 - academic.oup.com
Introduction: Tobacco smoke contains more than 7,000 chemicals, including known
carcinogens, such as tobacco-specific nitrosamines (TSNAs). TSNA levels in cigarettes vary …

Carcinogen exposure among Canadian tobacco users: changes in NNK exposure from 2007–2009 through 2012–2013

CD Czoli, D Hammond - Cancer Epidemiology, Biomarkers & Prevention, 2018 - AACR
Abstract Background: Tobacco-specific nitrosamines (TSNAs) are a class of carcinogens
found in tobacco products, whose levels can vary considerably depending on tobacco …

Tobacco-specific nitrosamines (NNAL, NNN, NAT, and NAB) exposures in the US Population Assessment of Tobacco and Health (PATH) Study Wave 1 (2013–2014)

B Xia, BC Blount, T Guillot, C Brosius… - Nicotine and …, 2021 - academic.oup.com
Introduction The tobacco-specific nitrosamines (TSNAs) are an important group of
carcinogens found in tobacco and tobacco smoke. To describe and characterize the levels …

[HTML][HTML] TSNA exposure from cigarette smoking: 18 years of urinary NNAL excretion data

S Appleton, RM Olegario, PJ Lipowicz - Regulatory toxicology and …, 2014 - Elsevier
The objective of this work was to characterize trends over time in urinary excretion of 4-
(methylnitrosamino)-1-(3-pyridyl)-1-butanol (NNAL) among cigarette smokers in the US. We …

Effect of differing levels of tobacco-specific nitrosamines in cigarette smoke on the levels of biomarkers in smokers

DL Ashley, RJ O'Connor, JT Bernert, CH Watson… - … , biomarkers & prevention, 2010 - AACR
Background: Smokers are exposed to significant doses of carcinogens, including tobacco-
specific nitrosamines (TSNA). Previous studies have shown significant global differences in …

Trends over time in tobacco-specific nitrosamines (TSNAs) in whole tobacco and smoke emissions from cigarettes sold in Canada

CD Czoli, D Hammond - Nicotine and Tobacco Research, 2018 - academic.oup.com
Abstract Introduction Tobacco-specific nitrosamines (TSNAs) are potent carcinogens. Levels
of TSNAs can be modified through manufacturing practices. In the 2000s, TSNA levels in …

Determination of tobacco-specific N-nitrosamines in urine of smokers and non-smokers

D Kavvadias, G Scherer, F Cheung, G Errington… - Biomarkers, 2009 - Taylor & Francis
Tobacco-specific N-nitrosamines (TSNA) include 4-(methylnitrosamino)-1-(3-pyridyl)-1-
butanone (NNK), N′-nitroso nornicotine (NNN), N′-nitroso anabasine (NAB) and N …

Tobacco-specific nitrosamines in tobacco from US brand and non-US brand cigarettes

DL Ashley, MD Beeson, DR Johnson… - Nicotine & tobacco …, 2003 - academic.oup.com
Tobacco-specific nitrosamines (TSNAs) are one of the major classes of carcinogens found in
tobacco products. As part of collaborative efforts to reduce tobacco use and resulting …

Exposure to tobacco-specific Nitrosamines among people who vape, smoke, or do neither: a systematic review and meta-analysis

E Taylor, E Simonavičius, A McNeill… - Nicotine and …, 2024 - academic.oup.com
Introduction Smoking exposes people to high levels of Tobacco-Specific Nitrosamines
(TSNAs), which include potent carcinogens. We systematically reviewed TSNA exposure …

Tobacco-specific nitrosamine 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol (NNAL) in smokers in the United States: NHANES 2007–2008

Y Xia, JT Bernert, RB Jain, DL Ashley, JL Pirkle - Biomarkers, 2011 - Taylor & Francis
The tobacco-specific carcinogen 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol (NNAL), a
metabolite of the tobacco-specific nitrosamine (TSNA) 4-(methylnitrosamino)-1-(3-pyridyl)-1 …