Regulatory T (Tregs) cells play a crucial role in immunoregulation and promotion of
immunological tolerance. Adoptive transfer of these cells has therefore been of interest in …

Recently, a new discipline termed “immunometabolism” has transformed the field of
immunology. It encompasses the study of the intrinsic metabolic pathways of different …

Regulatory T cells (Tregs) are an immunosuppressive subgroup of CD4+ T cells which are
identified by the expression of forkhead box protein P3 (Foxp3). The modulation capacity of …

Abstract Both Foxp3+ CD4+ regulatory T cells (Treg cells) and local immune responses in
nonlymphoid tissues have long been recognized as important elements of a well …

Regulatory T cells (Treg) are important in maintaining immune homeostasis and in
regulating a variety of immune responses, making them attractive targets for modulating …

Abstract Forkhead box P3 (FOXP3)+ regulatory T (TReg) cells prevent autoimmune disease,
maintain immune homeostasis and modulate immune responses during infection. To …

Regulatory T cells (Tregs) are critical for tolerance in humans. The exact mechanisms by
which the loss of peripheral tolerance leads to the development of autoimmunity and the …

Abstract Foxp3 expressing CD4+ CD25+ regulatory T cells (Tregs) have been shown to
prevent allograft rejection in clinical and animal models of transplantation. However, the role …

Although cluster of differentiation (CD) 8+ regulatory T (Treg) cells have been in the last 20
years more studied since evidences of their role in tolerance as been demonstrated in …

Development of naturally occurring CD4+ CD25+ T regulatory cells (Treg) in the thymus
requires the transcription factor Foxp3. Major histocompatibility complex (MHC) class II, self …