Brain is a vital organ of the human body which performs very important functions such as
analysis, processing, coordination, and execution of electrical signals. For this purpose, it …

Sphingolipids are highly enriched in the nervous system where they are pivotal constituents
of the plasma membranes and are important for proper brain development and functions …

Sphingolipids are polar membrane lipids present as minor components in eukaryotic cell
membranes. Sphingolipids are highly enriched in nervous cells, where they exert important …

Sphingolipids are complex lipids. They play a structural role in neurons, but are also
involved in regulating cellular communication, and neuronal differentiation and maturation …

Neurodegenerative diseases represent a class of fatal brain disorders for which the number
of effective therapeutic options remains limited with only symptomatic treatment accessible …

Cognitive processes, particularly learning and memory, are crucial brain mechanisms
mediating the successful adaptation of individuals to constantly changing environmental …

Over the past decade, it was found that relatively simple sphingolipids, such as ceramide,
sphingosine, sphingosine-1-phosphate, and glucosylceramide play important roles in …

Multiple sclerosis (MS) represents the most common demyelinating disease affecting the
central nervous system (CNS) in adults as well as in children. Furthermore, in children, in …

Sphingolipids are a class of lipids highly enriched in the central nervous system (CNS),
which shows great diversity and complexity, and has been implicated in CNS development …

Cholesterol is an essential component for neuronal physiology not only during development
stage but also in the adult life. Cholesterol metabolism in brain is independent from that in …