Serum concentrations of fibroblast growth factor 21 are elevated in patients with congenital or acquired lipodystrophy

K Miehle, T Ebert, S Kralisch, A Hoffmann, J Kratzsch… - Cytokine, 2016 - Elsevier
Objective Patients with lipodystrophy (LD) suffer from loss of subcutaneous adipose tissue
accompanied by dysregulation of several adipocyte-secreted factors. However, regulation of …

Serum FGF21 levels are elevated in association with lipodystrophy, insulin resistance and biomarkers of liver injury in HIV-1-infected patients

P Domingo, JM Gallego-Escuredo, JC Domingo… - Aids, 2010 - journals.lww.com
Objective: HIV-1-infected patients with lipodystrophy show insulin resistance, dyslipidemia
and other signs of metabolic syndrome. Fibroblast growth factor-21 (FGF21) is a novel …

[HTML][HTML] Lipodystrophy HIV-related and FGF21: A new marker to follow the progression of lipodystrophy?

S Benedini, L Luzi - Journal of Translational Internal Medicine, 2016 - degruyter.com
Recently new evidence about fibroblast growth factor 21 (FGF21) highlights the
opportunities to use this molecule in new pharmaceutical formulations to combat type 2 …

Serum concentrations and tissue expression of a novel endocrine regulator fibroblast growth factor‐21 in patients with type 2 diabetes and obesity

M Mraz, M Bartlova, Z Lacinova… - Clinical …, 2009 - Wiley Online Library
Objective Fibroblast growth factor‐21 (FGF21) is a novel endocrine and paracrine regulator
of metabolic homeostasis. The aim of our study was to measure its serum concentrations in …

[HTML][HTML] Total serum FGF-21 levels positively relate to visceral adiposity differently from its functional intact form

L Crudele, O Garcia-Irigoyen, M Cariello… - Frontiers in …, 2023 - frontiersin.org
Objective Increased Fibroblast Growth Factor-21 (FGF-21) circulating levels have been
described in obesity. In this observational study, we analysed a group of subjects with …

Association of serum fibroblast growth factor 19 levels with visceral fat accumulation is independent of glucose tolerance status

X Hu, Q Xiong, Y Xu, X Zhang, X Pan, X Ma… - Nutrition, Metabolism …, 2018 - Elsevier
Background and aims Recent studies suggested that circulating fibroblast growth factor
(FGF) 19 levels might be associated with the fat content and distribution, and varied with …

Fibroblast growth factor 21 levels are increased in nonalcoholic fatty liver disease patients and are correlated with hepatic triglyceride

H Li, Q Fang, F Gao, J Fan, J Zhou, X Wang… - Journal of …, 2010 - Elsevier
BACKGROUND & AIMS: Fibroblast growth factor 21 (FGF21), a hormone primarily secreted
by the liver in response to peroxisome proliferator-activated receptor-α (PPARα) activation …

[HTML][HTML] Circulating FGF21 in humans is potently induced by short term overfeeding of carbohydrates

AM Lundsgaard, AM Fritzen, KA Sjøberg, LS Myrmel… - Molecular …, 2017 - Elsevier
Objective Fibroblast-growth factor 21 (FGF21) is thought to be important in metabolic
regulation. Recently, low protein diets have been shown to increase circulating FGF21 …

Serum FGF21 levels are increased in obesity and are independently associated with the metabolic syndrome in humans

X Zhang, DCY Yeung, M Karpisek, D Stejskal… - Diabetes, 2008 - Am Diabetes Assoc
OBJECTIVE—Fibroblast growth factor 21 (FGF21) is a metabolic regulator with multiple
beneficial effects on glucose homeostasis and insulin sensitivity in animal models. This …

Plasma fibroblast growth factor 21 levels increase with ectopic fat accumulation and its receptor levels are decreased in the visceral fat of patients with type 2 diabetes

ES Hong, C Lim, HY Choi, YK Lee, EJ Ku… - BMJ Open Diabetes …, 2019 - drc.bmj.com
Background Fibroblast growth factor 21 (FGF21) is a novel metabolic regulator that has
beneficial effects on glucose and lipid metabolism. However, plasma FGF21 levels are …