Mid-gestation stage mouse embryos were cultured utilizing a serum-free culture medium
prepared from commercially available stem cell media supplements in an oxygenated rolling …

Current in vitro culture methods for mouse embryos are critically dependent on specially
prepared rodent serum. Rodent serum requires careful preparation and stringent …

Since its development in the 1970's, whole embryo culture (WEC) has provided an important
method of growing and observing murine embryos ex utero. During WEC, embryos are …

Advancements in methods that enable in vitro culture of mammalian embryos have become
an essential way of investigating mammalian early embryonic development and modeling …

We know a great deal about the development of the mammalian embryo until the time that
the blastocyst implants into the uterus. With model organisms such as the mouse, we have …

Postimplantation mammalian embryo culture methods have been generally inefficient and
limited to brief periods after dissection out of the uterus. Platforms have been recently …

Mouse genetic approaches when combined with live imaging tools have the potential to
revolutionize our current understanding of mammalian biology. The availability and …

In vitro culture of whole mouse embryos enables the maintenance of growth and
morphogenesis of postimplantation embryos outside the uterine environment. This …

Human early embryonic development is the cornerstone of a healthy baby. Abnormal early
embryonic development may lead to developmental and pregnancy-related disorders …

Mouse genetic approaches when combined with live imaging tools are revolutionizing our
current understanding of mammalian developmental biology. The availability and …