Cholangiocarcinoma remained a severe threat to human health. Deciphering the genomic
and/or transcriptomic profiles of tumor has been proved to be a promising strategy for …

Background: Cholangiocarcinoma is characterized by significant cellular heterogeneity and
complex intercellular communication, which contribute to its progression and therapeutic …

Cholangiocarcinoma (CCA) is a group of malignancies emerging in the biliary tree and is
associated with a poor patient prognosis. Although the anatomical location is the only …

Cholangiocarcinoma (CCA) is a type of cancer with limited treatment options and a poor
prognosis. Although some important genes and pathways associated with CCA have been …

Background The molecular mechanisms of CC (cholangiocarcinoma) oncogenesis and
progression are poorly understood. This study aimed to determine the genome-wide …

The prognosis of cholangiocarcinoma remains poor. The heterogeneity of the tumor
ecosystem of cholangiocarcinoma plays a critical role in tumorigenesis and therapeutic …

Background & Aims Intrahepatic cholangiocarcinoma (ICC) is the second most common liver
malignancy. ICC typically features remarkable cellular heterogeneity and a dense stromal …

Purpose: To establish a clinically applicable genomic clustering system, we investigated the
interactive landscape of driver mutations in intrahepatic cholangiocarcinoma (ICC) …

Aim Cholangiocarcinoma (CCA) is a highly malignant tumor found in the bile duct epithelial
cells, and the second most common primary tumor of the liver. However, the pivotal roles of …

Cholangiocarcinoma (CCA) comprises a heterogeneous collection of malignancies arising
within the biliary tract, characterized by late diagnosis, innate chemoresistance, and …