Insulin-like growth factor 1 (IGF-1) has neuroprotective actions, including vasodilatory, anti-
inflammatory, and antithrombotic effects, following ischemic stroke. However, the molecular …

Acute ischemic stroke is one of the main causes of mortality and morbidity worldwide. The
present study aimed to explore the effects of exogenous insulin-like growth factor 1 (IGF-1) …

Current studies demonstrated that cell survival is determined by a balance among signaling
cascades, including those that recruit the Akt and JNK pathways. In our present work, the …

We and others have shown that insulin-like growth factor-1 (IGF-1) is neuroprotective when
administered systemically shortly following stroke. In the current study, we addressed the …

Abstract Interleukin-4 (IL-4) has a protective effect against cerebral ischemia/reperfusion
injury. Animal experiments have shown that IL-4 improves the short-and long-term prognosis …

Post-stroke systemic injections of insulin-like growth factor-1 (IGF-1) exert neuroprotective
effects in rats. In the current study, we aimed to test the efficacy of IGF-1 neuroprotection in …

Insulin-like growth factor-1 (IGF-1) was suggested as a potential neuroprotective treatment
for traumatic brain injury (TBI) induced damage (cognitive as well as cellular). The main goal …

Ischemic stroke is a leading cause of death and disability, as therapeutic options for
mitigating the long-term deficits precipitated by the event remain limited. Acute …

Insulin‐like growth factor (IGF)‐1 is essential for the development of the nervous system, and
is present in many cell types. Relatively little is known about IGF‐1 expression in brain …

Background: Hundreds of previous studies demonstrated the cytoprotective effect of
trichostatin-A (TSA), a kind of histone deacetylases inhibitors (HDACIs), against cerebral …