The intermediate compartment (IC) is a pleiomorphic membrane system that mediates two-
way trafficing in the early biosynthetic-secretory pathway of mammalian cells. The IC …

The intermediate compartment (IC) between the endoplasmic reticulum (ER) and the Golgi
apparatus appears to constitute an autonomous organelle composed of spatially and …

Despite its discovery more than three decades ago and well-established role in protein
sorting and trafficking in the early secretory pathway, the intermediate compartment (IC) has …

In higher eukaryotic cells pleiomorphic compartments composed of vacuoles, tubules and
vesicles move from the endoplasmic reticulum (ER) and the plasma membrane to the cell …

Because the functional borders of the intermediate compartment (IC) are not well defined,
the spatial map of the transport machineries operating between the endoplasmic reticulum …

Publisher Summary The organized and characteristic elements of the Golgi complex (GC)
are the stacked smooth-surfaced cisternae, which are found in the centrosphere of all …

Each organelle of the secretory pathway is required to selectively allow transit of newly
synthesized secretory and plasma membrane proteins and also to maintain a unique set of …

INTRACELLUIAR ORGANELLES of higher eukaryotic cells are defined by their
characteristic morphology and the presence of resident membrane and lumenal marker …

Integrating the pleomorphic membranes of the intermediate compartment (IC) into the array
of Golgi cisternae is a crucial step in membrane transport, but it is poorly understood. To …

Vesicular traffic within the early secretory pathway is mediated by COPI–and COPII–coated
vesicles. While COPII–coated vesicles appear to be involved exclusively in the export of …