Liver plays a key role in glucose metabolism and homeostasis, and impaired hepatic
glucose metabolism contributes to the development of type 2 diabetes. However, the precise …

Objective Diabetes mellitus (DM) is a chronic disease characterized by hyperglycemia
resulting from defects in insulin secretion, insulin action, or both. The liver is a key organ …

Around 9% of the adult population in the world (463 million) suffer from diabetes mellitus.
Most of them (~ 90%) belong to type 2 diabetes mellitus (T2DM), which is a common chronic …

Abstract Aims/Introduction The incidence of type 2 diabetes is increasing worldwide. Hepatic
insulin resistance and liver lipid accumulation contributes to type 2 diabetes development …

Non-obese, spontaneous, and genetically predisposed type 2 diabetic Chinese hamsters
exhibit metabolic abnormalities similar to those observed in human T2DM. Here, tandem …

Food availability regulates basal metabolism and progression of many diseases, and liver
plays an important role in these processes. The effects of food availability on digital gene …

The main actions of metformin are as follows: To reduce hyperglycemia via the suppression
of gluconeogenesis, improve glucose uptake and insulin sensitivity, and stimulate activation …

Genetic and environmental factors such as high-fat diet are involved in the development of
type 2 diabetes mellitus (T2DM). Cynomolgus monkey shares similar genetic makeup, tissue …

Mouse is the most widely used animal model in biomedical research, but it remains
unknown what causes the large number of differentially regulated genes between human …

Differently Expressed Genes (DEGs) Relevant to Type 2 Diabetes Mellitus Identification and
Pathway Analysis via Integrated Bioinformatics Analysis - PMC Back to Top Skip to main content …