Inhaled medicines: past, present, and future

S Anderson, P Atkins, P Bäckman, D Cipolla… - Pharmacological …, 2022 - ASPET
The purpose of this review is to summarize essential pharmacological, pharmaceutical, and
clinical aspects in the field of orally inhaled therapies that may help scientists seeking to …

Emerging trends in inhaled drug delivery

AJ Hickey - Advanced drug delivery reviews, 2020 - Elsevier
Ideally, inhaled therapy is driven by the needs of specific disease management. Lung
biology interfaces with inhaler performance to allow optimal delivery of therapeutic agent for …

Back to the future: inhaled drug products

AJ Hickey - Journal of pharmaceutical sciences, 2013 - Elsevier
Inhaled therapeutic aerosols continue to be an important treatment for asthma and
pulmonary diseases. A variety of dosage forms are employed for different indications and …

Inhalation therapy: an historical review

M Sanders - Primary care respiratory journal, 2007 - nature.com
Inhalation has been employed as a method for delivering medications for more than two
thousand years, and the benefits of delivering medication directly to the affected site—the …

Pulmonary drug delivery. Part II: the role of inhalant delivery devices and drug formulations in therapeutic effectiveness of aerosolized medications

NR Labiris, MB Dolovich - British journal of clinical …, 2003 - Wiley Online Library
Research in the area of pulmonary drug delivery has gathered momentum in the last several
years, with increased interest in using the lung as a means of delivering drugs systemically …

The ascent of pulmonary drug delivery

I Gonda - Journal of pharmaceutical sciences, 2000 - Elsevier
The origins of inhalation therapy can be traced back to the early civilizations but this route of
administration was relatively uncommon until recently. Direct delivery of drugs to the lung by …

Pulmonary formulations: what remains to be done?

JG Weers, J Bell, HK Chan, D Cipolla… - Journal of Aerosol …, 2010 - liebertpub.com
Significant advances have been made in the last 50 years in developing safe and
efficacious aerosol formulations for pulmonary delivery. The key to future innovation may lie …

Drug delivery via the respiratory tract

PR Byron, JS PATTON - Journal of Aerosol medicine, 1994 - liebertpub.com
Inhalation offers an enormous absorptive surface area for rapid drug absorption and
substantial absorption of polypeptides. Due to slow clearance from the lower lung, even …

Inhaling medicines: delivering drugs to the body through the lungs

JS Patton, PR Byron - Nature reviews Drug discovery, 2007 - nature.com
Remarkably, with the exception of anaesthetic gases, the ancient human practice of inhaling
substances into the lungs for systemic effect has only just begun to be adopted by modern …

[HTML][HTML] Pulmonary delivery of biological drugs

W Liang, HW Pan, D Vllasaliu, JKW Lam - Pharmaceutics, 2020 - mdpi.com
In the last decade, biological drugs have rapidly proliferated and have now become an
important therapeutic modality. This is because of their high potency, high specificity and …