Tracking white and gray matter degeneration along the spinal cord axis in degenerative cervical myelopathy

K Vallotton, G David, M Hupp, N Pfender… - Journal of …, 2021 - liebertpub.com
This study aims to determine tissue-specific neurodegeneration across the spinal cord in
patients with mild-moderate degenerative cervical myelopathy (DCM). Twenty-four mild …

[HTML][HTML] Cortical volume reductions as a sign of secondary cerebral and cerebellar impairment in patients with degenerative cervical myelopathy

K Jütten, V Mainz, GA Schubert, RF Gohmann… - NeuroImage: Clinical, 2021 - Elsevier
This study investigated supra-and infratentorial structural gray and white matter (GM, WM)
alterations in patients with degenerative cervical myelopathy (DCM) as an indicator of …

[HTML][HTML] Monitoring for myelopathic progression with multiparametric quantitative MRI

AR Martin, B De Leener, J Cohen-Adad, S Kalsi-Ryan… - PLoS …, 2018 - journals.plos.org
Background Patients with mild degenerative cervical myelopathy (DCM) are often managed
non-operatively, and surgery is recommended if neurological progression occurs. However …

Cervical cord neurodegeneration in traumatic and non-traumatic spinal cord injury

M Seif, G David, E Huber, K Vallotton, A Curt… - Journal of …, 2020 - liebertpub.com
This study aimed to compare macrostructural and microstructural neurodegenerative
changes remote from a cervical spinal cord injury in traumatic spinal cord injury (tSCI) and …

[HTML][HTML] Tracking the neurodegenerative gradient after spinal cord injury

M Azzarito, M Seif, S Kyathanahally, A Curt… - NeuroImage: Clinical, 2020 - Elsevier
Objective To quantify neurodegenerative changes along the cervical spinal cord rostral to a
spinal cord injury (SCI) by means of quantitative MRI (qMRI) and to determine its …

The relationship between MRI signal intensity changes, clinical presentation, and surgical outcome in degenerative cervical myelopathy: analysis of a global cohort

A Nouri, AR Martin, S Kato, H Reihani-Kermani… - Spine, 2017 - journals.lww.com
Study Design. Retrospective analysis of prospective data. Objective. To assess the
relationship between MRI signal intensity changes, clinical presentation, and surgical …

Diffusion magnetic resonance imaging reveals tract‐specific microstructural correlates of electrophysiological impairments in non‐myelopathic and myelopathic spinal …

J Valošek, R Labounek, T Horák… - European Journal of …, 2021 - Wiley Online Library
Background and purpose Non‐myelopathic degenerative cervical spinal cord compression
(NMDC) frequently occurs throughout aging and may progress to potentially irreversible …

Extent of cord pathology in the lumbosacral enlargement in non-traumatic versus traumatic spinal cord injury

G David, K Vallotton, M Hupp, A Curt… - Journal of …, 2022 - liebertpub.com
This study compares remote neurodegenerative changes caudal to a cervical injury in
degenerative cervical myelopathy (DCM; ie, non-traumatic) and incomplete traumatic spinal …

T1 mapping for microstructural assessment of the cervical spinal cord in the evaluation of patients with degenerative cervical myelopathy

G Baucher, H Rasoanandrianina… - American Journal …, 2021 - Am Soc Neuroradiology
BACKGROUND AND PURPOSE: Although current radiologic evaluation of degenerative
cervical myelopathy by conventional MR imaging accurately demonstrates spondylosis or …

Can microstructural MRI detect subclinical tissue injury in subjects with asymptomatic cervical spinal cord compression? A prospective cohort study

AR Martin, B De Leener, J Cohen-Adad, DW Cadotte… - BMJ open, 2018 - bmjopen.bmj.com
Objectives Degenerative cervical myelopathy (DCM) involves extrinsic spinal cord
compression causing tissue injury and neurological dysfunction. Asymptomatic spinal cord …