[HTML][HTML] MiR-15b is a key regulator of proliferation and apoptosis of chondrocytes from patients with condylar hyperplasia by targeting IGF1, IGF1R and BCL2
P Cao, Y Feng, M Deng, J Li, H Cai, Q Meng… - Osteoarthritis and …, 2019 - Elsevier
Objective This study aimed to explore potential microRNAs (miRNAs), which participate in
the pathological process of condylar hyperplasia (CH) through targeting specific proliferation …
the pathological process of condylar hyperplasia (CH) through targeting specific proliferation …
miR-296-5p inhibits IL-1β-induced apoptosis and cartilage degradation in human chondrocytes by directly targeting TGF-β1/CTGF/p38MAPK pathway
Z Cao, W Liu, X Qu, H Bi, X Sun, Q Yu, G Cheng - Cell Cycle, 2020 - Taylor & Francis
Osteoarthritis (OA) is characterized by apoptosis of chondrocytes and an imbalance of
extracellular matrix (ECM) synthesis and catabolism. Emerging evidence has demonstrated …
extracellular matrix (ECM) synthesis and catabolism. Emerging evidence has demonstrated …
Downregulation of microRNA-23b-3p alleviates IL-1β-induced injury in chondrogenic CHON-001 cells
Q Yang, Y Zhou, P Cai, W Fu, J Wang… - Drug Design …, 2019 - Taylor & Francis
Background Osteoarthritis (OA) is a common joint disease, which is characterized by
degradation of articular cartilage. Evidence indicated that miR-23b-3p was upregulated in …
degradation of articular cartilage. Evidence indicated that miR-23b-3p was upregulated in …
Potential of miR-25-3p in protection of chondrocytes: emphasis on osteoarthritis
X He, L Deng - Folia Histochemica et Cytobiologica, 2021 - journals.viamedica.pl
Introduction. Osteoarthritis (OA) is the most prevailing musculoskeletal dysfunction triggered
by lesions in synovial membranes and articular cartilage. MicroRNAs (miRNAs) have …
by lesions in synovial membranes and articular cartilage. MicroRNAs (miRNAs) have …
[HTML][HTML] miR-590-5p affects chondrocyte proliferation, apoptosis, and inflammation by targeting FGF18 in osteoarthritis
P Jiang, X Dou, S Li, Q Jia, P Ling, H Liu… - American Journal of …, 2021 - ncbi.nlm.nih.gov
Objective: To investigate the potential miRNA targeting FGF18, and its role in regulating the
proliferation, apoptosis and inflammation in human primary chondrocytes. Methods: The …
proliferation, apoptosis and inflammation in human primary chondrocytes. Methods: The …
miR-21-5p protects IL-1β-induced human chondrocytes from degradation
H Zhu, X Yan, M Zhang, F Ji, S Wang - Journal of Orthopaedic Surgery and …, 2019 - Springer
Objective Osteoarthritis (OA) is a prevalent degenerative disease caused by various factors.
MicroRNAs are important regulators in OA. MiR-21-5p expression is decreased in OA …
MicroRNAs are important regulators in OA. MiR-21-5p expression is decreased in OA …
miR-211-5p contributes to chondrocyte differentiation by suppressing Fibulin-4 expression to play a role in osteoarthritis
H Liu, J Luo - The journal of biochemistry, 2019 - academic.oup.com
MicroRNAs (miRNAs) serve as key regulators in human disorders. Previous research
reported that miR-211-5p is down-regulated in osteoarthritis (OA) and that Fibulin-4 inhibits …
reported that miR-211-5p is down-regulated in osteoarthritis (OA) and that Fibulin-4 inhibits …
[HTML][HTML] Effects of miR-145 on the inhibition of chondrocyte proliferation and fibrosis by targeting TNFRSF11B in human osteoarthritis
GD Wang, XW Zhao, YG Zhang… - Molecular …, 2017 - spandidos-publications.com
Osteoarthritis (OA) is a common cause of functional deterioration in older adults, and altered
chondrogenesis is the most common pathophysiological process involved in the …
chondrogenesis is the most common pathophysiological process involved in the …
MicroRNA‐29b regulates hypertrophy of murine mesenchymal stem cells induced toward chondrogenesis
C Zhao, Y Miao, Z Cao, J Shi, J Li… - Journal of Cellular …, 2019 - Wiley Online Library
Objective Chondrocyte hypertrophy, a terminal stage of chondrocyte differentiation, is
essential to the endochondral bone formation and is one of the major pathological factors in …
essential to the endochondral bone formation and is one of the major pathological factors in …
miR-27b promotes type II collagen expression by targetting peroxisome proliferator-activated receptor-γ2 during rat articular chondrocyte differentiation
J Xu, S Lv, Y Hou, K Xu, D Sun, Y Zheng… - Bioscience …, 2018 - portlandpress.com
MicroRNAs (miRNAs) play an essential role in articular cartilage development and growth.
However, the exact mechanisms involved in this process remain unknown. In the present …
However, the exact mechanisms involved in this process remain unknown. In the present …