Association of sleep, neuropsychological performance, and gray matter volume with glymphatic function in community-dwelling older adults

TY Siow, CH Toh, JL Hsu, GH Liu, SH Lee, NH Chen… - Neurology, 2022 - AAN Enterprises
Background and Objectives The glymphatic system, which is robustly enabled during some
stages of sleep, is a fluid-transport pathway that clears cerebral waste products. Most …

The impact of sleep components, quality and patterns on glymphatic system functioning in healthy adults: a systematic review

L Sangalli, IA Boggero - Sleep Medicine, 2023 - Elsevier
Objective The glymphatic system is thought to be responsible for waste clearance in the
brain. As it is primarily active during sleep, different components of sleep, subjective sleep …

[HTML][HTML] The sleeping brain: harnessing the power of the glymphatic system through lifestyle choices

OC Reddy, YD van der Werf - Brain sciences, 2020 - mdpi.com
The glymphatic system is a “pseudo-lymphatic” perivascular network distributed throughout
the brain, responsible for replenishing as well as cleansing the brain. Glymphatic clearance …

The glymphatic system and waste clearance with brain aging: a review

H Benveniste, X Liu, S Koundal, S Sanggaard, H Lee… - Gerontology, 2019 - karger.com
The glymphatic system is a glial-dependent waste clearance pathway in the brain, in place
of lymphatic vessels, dedicated to drain away soluble waste proteins and metabolic …

Association of cognition and brain reserve in aging and glymphatic function using diffusion tensor image-along the perivascular space (DTI-ALPS)

WC Hsiao, HI Chang, SW Hsu, CC Lee, SH Huang… - Neuroscience, 2023 - Elsevier
The glymphatic system is a fluid-clearance pathway that clears cerebral waste products, and
its dysfunction has been associated with protein aggregation diseases such as Alzheimer's …

Association of MRI indices of glymphatic system with amyloid deposition and cognition in mild cognitive impairment and Alzheimer disease

K Kamagata, C Andica, K Takabayashi, Y Saito… - Neurology, 2022 - AAN Enterprises
Background and Objectives The glymphatic system is a whole-brain perivascular network,
which promotes CSF/interstitial fluid exchange. Alterations to this system may play a pivotal …

[HTML][HTML] Impaired glymphatic system actions in obstructive sleep apnea adults

B Roy, A Nunez, RS Aysola, DW Kang… - Frontiers in …, 2022 - frontiersin.org
Study Objectives Obstructive sleep apnea (OSA) is accompanied by sleep fragmentation
and altered sleep architecture, which can potentially hinder the glymphatic system …

Sleep, cerebrospinal fluid, and the glymphatic system: A systematic review

PLH Chong, D Garic, MD Shen, I Lundgaard… - Sleep medicine …, 2022 - Elsevier
Current theories of the glymphatic system (GS) hypothesize that it relies on cerebrospinal
fluid (CSF) circulation to disseminate growth factors and remove metabolic waste from the …

Magnetic resonance images implicate that glymphatic alterations mediate cognitive dysfunction in Alzheimer disease

JL Hsu, YC Wei, CH Toh, IT Hsiao, KJ Lin… - Annals of …, 2023 - Wiley Online Library
Objective The glymphatic system cleans amyloid and tau proteins from the brain in animal
studies of Alzheimer disease (AD). However, there is no direct evidence showing this in …

Glymphatic system impairment in Alzheimer's disease and idiopathic normal pressure hydrocephalus

BC Reeves, JK Karimy, AJ Kundishora, H Mestre… - Trends in molecular …, 2020 - cell.com
Approximately 10% of dementia patients have idiopathic normal pressure hydrocephalus
(iNPH), an expansion of the cerebrospinal fluid (CSF)-filled brain ventricles. iNPH and …