The largely nuclear cap-binding complex (CBC) binds to the 5′ caps of RNA polymerase II
(RNAPII)-synthesized transcripts and serves as a dynamic interaction platform for a myriad …

The nuclear cap–binding complex (CBC) stimulates multiple steps in several RNA
maturation pathways, but how it functions in humans is incompletely understood. For small …

The 5′ mRNA cap structure is essential for efficient gene expression from yeast to human. It
plays a critical role in all aspects of the life cycle of an mRNA molecule. Capping occurs co …

Every RNA polymerase II transcript receives a 5′-end 7-methylguanosine (m7G) cap,
which is rapidly bound by the nuclear cap–binding complex (CBC). Two recent studies now …

Nuclear cap binding complex (CBC) is recruited cotranscriptionally and stimulates
spliceosome assembly on nascent mRNAs; however, its possible functions in regulating …

The nuclear cap-binding complex (CBC) coordinates co-transcriptional maturation,
transport, or degradation of nascent RNA polymerase II (Pol II) transcripts. CBC with its …

The nuclear cap-binding complex (CBC) stimulates processing reactions of capped RNAs,
including their splicing, 3′-end formation, degradation, and transport. CBC effects are …

Abstract The nuclear Cap-Binding Complex (CBC), consisting of Nuclear Cap-Binding
Protein 1 (NCBP1) and 2 (NCBP2), associates with the nascent 5′ cap of RNA polymerase …

The 5′ cap structure is added onto RNA polymerase II transcripts soon after initiation of
transcription and modulates several post‐transcriptional regulatory events involved in RNA …

Promoter-proximal pausing of RNAPII coincides with the formation of the cap structure at the
5′ end of pre-mRNA, which is bound by the cap-binding protein complex (CBC). Although …