Serum thiols and cardiovascular risk scores: a combined assessment of transsulfuration pathway components and substrate/product ratios

AA Mangoni, A Zinellu, C Carru, JR Attia… - Journal of Translational …, 2013 - Springer
Background Serum thiols have shown associations with surrogate markers of cardiovascular
disease. However, little information is available on their combined association with validated …

Serum free thiols predict cardiovascular events and all-cause mortality in the general population: A prospective cohort study

AE Abdulle, AR Bourgonje, LM Kieneker, AM Koning… - BMC medicine, 2020 - Springer
Background Serum free thiols (R-SH, sulfhydryl groups) reliably reflect systemic oxidative
stress. Since serum free thiols are rapidly oxidized by reactive species, systemic oxidative …

Systemic transsulfuration pathway thiol concentrations in chronic obstructive pulmonary disease patients

A Zinellu, E Zinellu, E Sotgiu, AG Fois… - European Journal of …, 2020 - Wiley Online Library
Background It is amply reported that patients with chronic obstructive pulmonary disease
(COPD) have increased risk of cardiovascular disease (CVD). Recent evidence suggests …

The association of fasting plasma sulfur-containing compounds with BMI, serum lipids and apolipoproteins

AK Elshorbagy, M Valdivia-Garcia, IM Graham… - Nutrition, Metabolism …, 2012 - Elsevier
BACKGROUND AND AIM: Sulfur amino acids are recognized as potent modulators of lipid
metabolism. Plasma total cysteine (tCys) is associated with fat mass, obesity and serum LDL …

Urinary excretion of sulfur metabolites and risk of cardiovascular events and all-cause mortality in the general population

JC van den Born, ARS Frenay, AM Koning… - Antioxidants & redox …, 2019 - liebertpub.com
Aims: Thiosulfate and sulfate are metabolites of hydrogen sulfide (H2S), a gaseous
signaling molecule with cardiovascular (CV) protective properties. Urinary thiosulfate …

Hyperhomocysteinemia is a biomarker of sulfur-deficiency in human morbidities

Y Ingenbleek - The Open Clinical Chemistry Journal, 2009 - benthamopen.com
Methionine (Met) is crucially involved in the synthesis of S-compounds endowed with
molecular, structural and functional properties of survival value. Dietary Met may undergo …

[HTML][HTML] Lifestyle and cardiovascular disease risk factors as determinants of total cysteine in plasma: the Hordaland Homocysteine Study

L El-Khairy, PM Ueland, O Nygård, H Refsum… - The American journal of …, 1999 - Elsevier
Background Plasma total homocysteine (tHcy) is a cardiovascular disease risk factor and is
related to several components of the established cardiovascular disease risk profile …

Implications of plasma thiol redox in disease

PVS Oliveira, FRM Laurindo - Clinical Science, 2018 - portlandpress.com
Thiol groups are crucially involved in signaling/homeostasis through oxidation, reduction,
and disulphide exchange. The overall thiol pool is the resultant of several individual pools of …

Systemic oxidative stress, aging and the risk of cardiovascular events in the general female population

MF Bourgonje, AR Bourgonje, AE Abdulle… - Frontiers in …, 2021 - frontiersin.org
Introduction: Menopause is associated with increased cardiovascular risk, in which oxidative
stress plays a pivotal role. Systemic oxidative stress is reflected by decreased levels of free …

[HTML][HTML] Metabolomic evaluation of the consequences of plasma cystathionine elevation in adults with stable angina pectoris

BN DeRatt, MA Ralat, V Lysne, F Tayyari, I Dhar… - The Journal of …, 2017 - Elsevier
Background An elevated circulating cystathionine concentration, which arises in part from
insufficiencies of vitamin B-6, B-12, or folate, has been shown to be associated with …