The results of numerous long-term, randomized trials show that statins significantly decrease
the risks of myocardial infarction, stroke, and vascular death as well as total mortality. The …

Until recently, atorvastatin was known only as a new but more potent statin ('me too'drug) for
lowering low-density lipoprotein cholesterol. In the last 2 years, data has become available …

The underlying disorder in the vast majority of cases of cardiovascular disease is
atherosclerosis, for which low-density lipoprotein cholesterol is recognized as a major risk …

Background: Since the 1990s a multitude of statin trials have definitively demonstrated the
ability of statin therapy to reduce the risk of adverse coronary heart disease (CHD) events …

Evidence is mounting that 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitors
(statins) have a number of pleiotropic effects over and above their lipid-lowering properties …

Placebo-controlled clinical trials have shown that atorvastatin is beneficial in patients with
myocardial ischemia, established coronary artery disease, hypertension and 3 other …

Atorvastatin has been extensively studied in the primary and secondary prevention of
cardiovascular events, and may have some clinical advantages over various other statins in …

The introduction of statins has drastically changed the treatment and prevention of
atherosclerotic vascular disease. By lowering lipid levels and reducing the risk of coronary …

The identification and treatment of dyslipidemia is a critical component of ongoing efforts to
reduce the incidence of atherosclerotic disease in both men and women. Several recent …

Statins safely and effectively reduce the morbidity and mortality due to cardiovascular
disease. In the trials conducted so far, which have been carried out predominantly on high …