Orthodontic force induces nerve injury-like transcriptomic changes driven by TRPV1-expressing afferents in mouse trigeminal ganglia
S Wang, MK Chung - Molecular Pain, 2020 - journals.sagepub.com
Orthodontic force produces mechanical irritation and localized inflammation in the
periodontium, which causes pain in most patients. Nocifensive behaviors resulting from …
periodontium, which causes pain in most patients. Nocifensive behaviors resulting from …
[HTML][HTML] TRPV1 and TRPV1-expressing nociceptors mediate orofacial pain behaviors in a mouse model of orthodontic tooth movement
S Wang, M Kim, Z Ali, K Ong, EK Pae… - Frontiers in …, 2019 - frontiersin.org
Orthodontic force produces mechanical irritation and inflammation in the periodontium,
which is inevitably accompanied by pain. Despite its prevalence, treatment of orthodontic …
which is inevitably accompanied by pain. Despite its prevalence, treatment of orthodontic …
Varied temporal expression patterns of trigeminal TRPA1 and TRPV1 and the neuropeptide CGRP during orthodontic force-induced pain
P Thammanichanon, A Kaewpitak, T Binlateh… - Archives of Oral …, 2021 - Elsevier
Objective The aim of this study was to quantify the temporal changes in inflammation and
TRPA1, TRPV1 and CGRP expression in the trigeminal ganglion during force-induced …
TRPA1, TRPV1 and CGRP expression in the trigeminal ganglion during force-induced …
[HTML][HTML] Nociceptor mechanisms underlying pain and bone remodeling via orthodontic forces: toward no pain, big gain
Orthodontic forces are strongly associated with pain, the primary complaint among patients
wearing orthodontic braces. Compared to other side effects of orthodontic treatment …
wearing orthodontic braces. Compared to other side effects of orthodontic treatment …
Blocking of TRPV-1 in the parodontium relieves orthodontic pain by inhibiting the expression of TRPV-1 in the trigeminal ganglion during experimental tooth …
Y Gao, Y Liu, K Zhu, Z Zhang, H Qiao, Z Lu, T Zhong… - Neuroscience …, 2016 - Elsevier
Orthodontic pain has confused the orthodontics for a long time, and recent research
demonstrated that transient receptor potential vanilloid type 1 (TRPV1) had crucial functions …
demonstrated that transient receptor potential vanilloid type 1 (TRPV1) had crucial functions …
Orthodontic force-induced oxidative stress in the periodontal tissue and dental pulp elicits nociception via activation/sensitization of TRPA1 on nociceptive fibers
A Morii, Y Miyamura, MI Sago, M Mizuhara… - Free radical Biology and …, 2020 - Elsevier
Orthodontic patients complain of pain for the first few days after insertion of appliances.
Mechanical force has been reported to produce oxidants in periodontal ligament (PDL) cells …
Mechanical force has been reported to produce oxidants in periodontal ligament (PDL) cells …
Increased expression of TRPV1 in the trigeminal ganglion is involved in orofacial pain during experimental tooth movement in rats
H Qiao, YN Gao, C Zhang… - European Journal of Oral …, 2015 - Wiley Online Library
To investigate whether transient receptor potential vanilloid type 1 (TRPV 1) is involved in
pain induced by experimental tooth movement, experiments were performed in male S …
pain induced by experimental tooth movement, experiments were performed in male S …
[HTML][HTML] Differential Changes in TRPV1 expression after trigeminal sensory nerve injury
We have recently demonstrated that inferior alveolar nerve and mental nerve (branches of
the mandibular nerve) injury from rats serves as a valid trigeminal neuropathic pain model …
the mandibular nerve) injury from rats serves as a valid trigeminal neuropathic pain model …
Occlusal trauma induces neuroimmune crosstalk for a pain state
HB Abdalla, MH Napimoga… - Journal of Dental …, 2022 - journals.sagepub.com
Temporomandibular joint (TMJ) disorder caused by occlusal trauma is one of the most
controversial topics in dentistry. Experimental traumatic occlusion (ETO) induced by metal …
controversial topics in dentistry. Experimental traumatic occlusion (ETO) induced by metal …
Neuronal plasticity of trigeminal ganglia in mice following nerve injury
Background Nerve injury may induce neuropathic pain. In studying the mechanisms of
orofacial neuropathic pain, attention has been paid to the plastic changes that occur in the …
orofacial neuropathic pain, attention has been paid to the plastic changes that occur in the …