Breast cancer; discovery of novel diagnostic biomarkers, drug resistance, and therapeutic implications

S Afzal, M Hassan, S Ullah, H Abbas… - Frontiers in molecular …, 2022 - frontiersin.org
Breast cancer is the second most reported cancer in women with high mortality causing
millions of cancer-related deaths annually. Early detection of breast cancer intensifies the …

circRNA-miRNA-mRNA in breast cancer

M Zhang, X Bai, X Zeng, J Liu, F Liu, Z Zhang - Clinica Chimica Acta, 2021 - Elsevier
Among cancers, breast cancer has the highest incidence rate among women and poses a
tremendous threat to women's health. Messenger RNA (mRNA), microRNA (miRNA) and …

[HTML][HTML] Roles of circular RNA in breast cancer: present and future

Z Li, Z Chen, G Hu, Y Jiang - American journal of translational …, 2019 - ncbi.nlm.nih.gov
Breast cancer is one of the most common cancers with the highest morbidity and mortality
among women despite the treatment approaches have advanced including surgery …

Predicting and overcoming chemotherapeutic resistance in breast cancer

KH Chun, JH Park, S Fan - Translational Research in Breast Cancer …, 2017 - Springer
Our understanding of breast cancer and its therapeutic approach has improved greatly due
to the advancement of molecular biology in recent years. Clinically, breast cancers are …

[HTML][HTML] The role of CircRNA/miRNA/mRNA axis in breast cancer drug resistance

MH Ghazimoradi, S Babashah - Frontiers in Oncology, 2022 - frontiersin.org
Multi-drug resistance is one of the major obstacles in the treatment of cancers. This
undesirable feature increases the mortality rate of cancers, including breast cancer …

Circular RNA: A potential diagnostic, prognostic, and therapeutic biomarker for human triple-negative breast cancer

T Tian, Y Zhao, J Zheng, S Jin, Z Liu, T Wang - Molecular Therapy-Nucleic …, 2021 - cell.com
Triple-negative breast cancer (TNBC), which is the most malignant subtype of breast cancer
(BC), accounts for 10%–20% of all BC cases. TNBC, which occurs more frequently in young …

[HTML][HTML] Circular RNAs in breast cancer diagnosis, treatment and prognosis

X Huang, C Song, J Zhang, L Zhu, H Tang - Oncology Research, 2024 - ncbi.nlm.nih.gov
Breast cancer has surpassed lung cancer to become the most common malignancy
worldwide. The incidence rate and mortality rate of breast cancer continue to rise, which …

Overview of the therapeutic strategies for ER positive breast cancer

B Blakely, S Shin, K Jin - Biochemical Pharmacology, 2023 - Elsevier
Estrogen Receptor is the driving transcription factor in about 75% of all breast cancers,
which is the target of endocrine therapies, but drug resistance is a common clinical problem …

Circular RNAs as potential biomarkers in breast cancer

FDE De Palma, F Salvatore, JG Pol, G Kroemer… - Biomedicines, 2022 - mdpi.com
Due to the high heterogeneity and initially asymptomatic nature of breast cancer (BC), the
management of this disease depends on imaging together with immunohistochemical and …

[HTML][HTML] CircRNA: a novel type of biomarker for cancer

H Zhang, L Jiang, D Sun, J Hou, Z Ji - Breast cancer, 2018 - Springer
Circular RNAs (circRNAs) are a class of long, non-coding RNAs molecules that shape a
covalently closed continuous loop which have no 5′–3′ polarity and contain no polyA tail …