Background Skeletal muscle deficits are associated with worse exercise performance in the
Fontan circulation and may be improved by exercise training. We aimed to assess the …

Background Patients with congenital heart disease (CHD)—including those after Fontan
operation—are encouraged to be physically active. Aim To prospectively determine the …

Objective Fontan survivors report reduced health-related quality of life (HRQOL) and have
decreased exercise tolerance compared to healthy peers. We recently demonstrated that a …

Aims Effective therapy to improve exercise capacity in Fontan patients is lacking. Leg-
focused high-weight resistance training might augment the peripheral muscle pump and …

Despite improvement in survival, patients with a Fontan circulation are at risk for numerous
complications, and exercise capacity and quality of life are usually reduced compared with …

Objective We previously described lower leg lean mass Z-scores (LLMZ) in Fontan patients
associated with worse peak oxygen consumption on metabolic exercise testing. We …

Objectives The peripheral muscle pump is key in promoting cardiac filling during exercise,
especially in subjects who lack a subpulmonary ventricle (the Fontan circulation). A muscle …

Background Peak oxygen uptake (peak VO 2) and its decline predict death or serious
cardiovascular adverse events in patients with Fontan circulation. Our aim was to study VO 2 …

In the pediatric population, exercise capacity differs between females and males and the
gap widens through adolescence. However, specific age-and sex-based changes in …

Patients with a Fontan circulation have impaired exercise capacity. Cardiac rehabilitation
(CR) has shown promise in enhancing peak exercise parameters in this population, but an …