[HTML][HTML] Low expression of G protein-coupled oestrogen receptor 1 (GPER) is associated with adverse survival of breast cancer patients
G protein-coupled oestrogen receptor 1 (GPER), also called G protein-coupled receptor 30
(GPR30), is attracting considerable attention for its potential role in breast cancer …
(GPR30), is attracting considerable attention for its potential role in breast cancer …
Cytoplasmic G protein-coupled estrogen receptor 1 as a prognostic indicator of breast cancer: a meta-analysis
D Zhang, J Wang, H Chen… - Technology in Cancer …, 2022 - journals.sagepub.com
Purpose: To determine whether G protein-coupled estrogen receptor 1 (GPER1) is a
suitable biomarker to predict the treatment outcome of breast cancer (BC). Methods: A meta …
suitable biomarker to predict the treatment outcome of breast cancer (BC). Methods: A meta …
G Protein–Coupled Estrogen Receptor Is Apoptotic and Correlates with Increased Distant Disease-Free Survival of Estrogen Receptor–Positive Breast Cancer …
S Broselid, B Cheng, M Sjöström, K Lövgren… - Clinical Cancer …, 2013 - AACR
Purpose: G protein–coupled estrogen receptor 1 (GPER1), previously named GPR30, is a
membrane receptor reported to mediate nongenomic estrogen responses. We investigated if …
membrane receptor reported to mediate nongenomic estrogen responses. We investigated if …
The cell surface estrogen receptor, G protein-coupled receptor 30 (GPR30), is markedly down regulated during breast tumorigenesis
I Poola, J Abraham, A Liu… - Breast cancer: basic …, 2008 - journals.sagepub.com
Background GPR30 is a cell surface estrogen receptor that has been shown to mediate a
number of non-genomic rapid effects of estrogen and appear to balance the signaling of …
number of non-genomic rapid effects of estrogen and appear to balance the signaling of …
[HTML][HTML] GPR30 expression and function in breast cancer cells are induced through a cis‑acting element targeted by ETS factors
D Segura‑Bautista, A Olivares… - Oncology …, 2020 - spandidos-publications.com
The capacity that G protein‑coupled receptor 30 (GPR30) has demonstrated for triggering
estrogen‑dependent signaling pathways has attracted the interest of breast cancer …
estrogen‑dependent signaling pathways has attracted the interest of breast cancer …
GPER function in breast cancer: an overview
R Lappano, A Pisano, M Maggiolini - Frontiers in endocrinology, 2014 - frontiersin.org
The G-protein-coupled estrogen receptor-1 (GPER, formerly known as GPR30) has attracted
increasing interest, considering its ability to mediate estrogenic signaling in different cell …
increasing interest, considering its ability to mediate estrogenic signaling in different cell …
The G protein–coupled receptor GPR30 inhibits proliferation of estrogen receptor–positive breast cancer cells
EA Ariazi, E Brailoiu, S Yerrum, HA Shupp, MJ Slifker… - Cancer research, 2010 - AACR
The G protein–coupled receptor GPR30 binds 17β-estradiol (E2) yet differs from classic
estrogen receptors (ERα and ERβ). GPR30 can mediate E2-induced nongenomic signaling …
estrogen receptors (ERα and ERβ). GPR30 can mediate E2-induced nongenomic signaling …
Distribution of GPR30, a seven membrane–spanning estrogen receptor, in primary breast cancer and its association with clinicopathologic determinants of tumor …
EJ Filardo, CT Graeber, JA Quinn, MB Resnick… - Clinical cancer …, 2006 - AACR
Purpose: The seven transmembrane receptor, GPR30, is linked to estrogen binding and
heparan-bound epidermal growth factor release. Here, the significance of GPR30 in human …
heparan-bound epidermal growth factor release. Here, the significance of GPR30 in human …
GPER mediates estrogen-induced signaling and proliferation in human breast epithelial cells and normal and malignant breast
AL Scaling, ER Prossnitz, HJ Hathaway - Hormones and Cancer, 2014 - Springer
Abstract 17β-Estradiol (estrogen), through receptor binding and activation, is required for
mammary gland development. Estrogen stimulates epithelial proliferation in the mammary …
mammary gland development. Estrogen stimulates epithelial proliferation in the mammary …
Lack of G protein-coupled estrogen receptor (GPER) in the plasma membrane is associated with excellent long-term prognosis in breast cancer
M Sjöström, L Hartman, D Grabau, T Fornander… - Breast cancer research …, 2014 - Springer
G protein-coupled estrogen receptor (GPER), or GPR30, is a membrane receptor reported to
mediate non-genomic estrogen responses. Tamoxifen is a partial agonist at GPER in vitro …
mediate non-genomic estrogen responses. Tamoxifen is a partial agonist at GPER in vitro …