Carthamus Tinctorius L. extract attenuates cardiac remodeling in L-NAME-induced hypertensive rats by inhibiting the NADPH oxidase-mediated TGF-β1 and MMP-9 …

S Bunbupha, P Pakdeechote, P Maneesai… - Annals Of Anatomy …, 2019 - Elsevier
Carthamus tinctorius L.(CT) has been widely used in Asian countries as a beverage and a
folk medicine. The current study investigates the effect of CT extract on cardiac remodeling …

Carthamus tinctorius L. extract improves hemodynamic and vascular alterations in a rat model of renovascular hypertension through Ang II-AT1R-NADPH oxidase …

S Bunbupha, C Wunpathe, P Maneesai… - Annals of Anatomy …, 2018 - Elsevier
Carthamus tinctorius L.(CT) is widely used in Asian countries as a beverage and in folk
medicine. The effects of CT extract on hemodynamics, vascular remodeling, the renin …

Synergistic Antihypertensive Effect of Carthamus tinctorius L. Extract and Captopril in l-NAME-Induced Hypertensive Rats via Restoration of eNOS and AT1R …

P Maneesai, P Prasarttong, S Bunbupha… - Nutrients, 2016 - mdpi.com
This study examined the effect of Carthamus tinctorius (CT) extract plus captopril treatment
on blood pressure, vascular function, nitric oxide (NO) bioavailability, oxidative stress and …

Clitoria ternatea (Linn.) flower extract attenuates vascular dysfunction and cardiac hypertrophy via modulation of Ang II/AT1R/TGF‐β1 cascade in hypertensive rats

P Maneesai, N Chaihongsa… - Journal of the …, 2022 - Wiley Online Library
BACKGROUND Clitoria ternatea (CT)(the Fabaceae family) has been reported to elicit
several biological responses, such as anti‐inflammation and anti‐depression effects. This …

[HTML][HTML] Tempol inhibits TGF-β and MMPs upregulation and prevents cardiac hypertensive changes

E Rizzi, MM Castro, CS Ceron, EM Neto-Neves… - International journal of …, 2013 - Elsevier
BACKGROUND: Increased oxidative stress upregulates matrix metalloproteinases (MMPs)
and transforming grow factor (TGF–β), which are involved in hypertensive cardiac …

LPS‐enhanced IGF‐IIR pathway to induce H9c2 cardiomyoblast cell hypertrophy was attenuated by Carthamus tinctorius extract via IGF‐IR activation

CL Tung, DJY Hsieh, R Baskaran, B Ban… - Environmental …, 2020 - Wiley Online Library
The use of herbs as alternative cardiovascular disease treatment has attracted a great deal
of attention owing to their lower toxicity. Whether Carthamus tinctorius extract prevent …

Butterfly Pea Flower (Clitoria ternatea Linn.) Extract Ameliorates Cardiovascular Dysfunction and Oxidative Stress in Nitric Oxide-Deficient Hypertensive Rats

P Maneesai, M Iampanichakul, N Chaihongsa… - Antioxidants, 2021 - mdpi.com
In this study, we examine whether Clitoria ternatea Linn.(CT) can prevent Nω-nitro-L-
arginine methyl ester hydrochloride (L-NAME)-induced cardiac and vascular dysfunction in …

Centella asiatica (L.) Urb. Prevents Hypertension and Protects the Heart in Chronic Nitric Oxide Deficiency Rat Model

MK Bunaim, Y Kamisah, MN Mohd Mustazil… - Frontiers in …, 2021 - frontiersin.org
Background: Hypertension is a major risk factor for cardiovascular disease (CVD), which is
the number one cause of global mortality. The potential use of natural products to alleviate …

Clitoria ternatea L. extract prevents kidney damage by suppressing the Ang II/Nox4/oxidative stress cascade in l-NAME-induced hypertension model of rats

B Saengnak, P Kanla, R Samrid, T Berkban… - Annals of Anatomy …, 2021 - Elsevier
Clitoria ternatia L.(CT) has been reported to have anti-inflammatory and antioxidant effects.
This study investigated the effect of CT aqueous flower extract on blood pressure and renal …

L-carvone attenuates myocardial injury and dyslipidemia in rats with isoproterenolinduced cardiac hypertrophy

A Nagarajan, VA Doss - Asian Pacific Journal of Tropical …, 2023 - journals.lww.com
Objective: To explore the therapeutic efficacy of L-carvone from Mentha spicata L. leaf
extracts against isoproterenol-induced cardiac hypertrophy in rats. Methods: Isoproterenol (5 …