Natural history of hepatic and extrahepatic hepatitis C virus diseases and impact of interferon-free HCV therapy

F Negro - Cold Spring Harbor perspectives in …, 2020 - perspectivesinmedicine.cshlp.org
The hepatitis C virus (HCV) infects 71.1 million persons and causes 400,000 deaths
annually worldwide. HCV mostly infects the liver, causing acute and chronic …

[HTML][HTML] Hepatitis C virus: A time for decisions. Who should be treated and when?

BM Attar, DH Van Thiel - World journal of gastrointestinal …, 2016 - ncbi.nlm.nih.gov
Cirrhosis is the most important risk factor for hepatocellular carcinoma (HCC) regardless of
the etiology of cirrhosis. Compared to individuals who are anti-hepatitis C virus (HCV) …

The end of the hepatitis C burden: Really?

JM Pawlotsky - Hepatology, 2016 - journals.lww.com
Chronic infection with the hepatitis C virus (HCV) is a leading cause of chronic liver disease
and its complications, including cirrhosis, decompensated cirrhosis, hepatocellular …

Hepatitis C cure with antiviral therapy–benefits beyond the liver

V Soriano, P Labarga… - Antiviral …, 2016 - journals.sagepub.com
Liver disease is the major complication of chronic HCV infection. However, extrahepatic
complications are common (50–75%), including mixed cryoglobulinaemia and B-cell …

Changes in clinical scenarios, management, and perspectives of patients with chronic hepatitis C after viral clearance by direct-acting antivirals

R Nevola, L Rinaldi, L Zeni, C Romano… - Expert Review of …, 2021 - Taylor & Francis
ABSTRACT Introduction Hepatitis C virus (HCV) causes a systemic infection inducing
hepatic and extrahepatic diseases. These latter involve cardiovascular system, kidney …

Extrahepatic manifestations of HCV: the role of direct acting antivirals

ML Polo, N Laufer - Expert review of anti-infective therapy, 2017 - Taylor & Francis
ABSTRACT Introduction: Hepatitis C virus (HCV) represents a major health concern, as
nearly 3 million people become newly infected by this pathogen annually. The majority of …

[HTML][HTML] Going viral: why eliminating the burden of hepatitis C requires enhanced cooperation between specialists and primary care providers

R Fox - Digestive Diseases and Sciences, 2016 - Springer
It has long been recognized that when a sustained virological response (SVR) occurs after
antiviral treatment for chronic hepatitis C virus (HCV), there is a reduced risk of cirrhosis …

Hepatitis C virus epidemiology and the impact of interferon-free hepatitis C virus therapy

JV Lazarus, E Roel… - Cold Spring …, 2020 - perspectivesinmedicine.cshlp.org
The public health impact of hepatitis C virus (HCV) infection has been realized only recently.
Globally, 71 million people are living with HCV chronic infection. HCV prevalence is higher …

The benefits of hepatitis C virus cure: every rose has thorns

D Salmon, MU Mondelli, M Maticic… - Journal of viral …, 2018 - Wiley Online Library
To examine mid‐term benefits on hepatic complications, extrahepatic clinical syndromes
and quality of life associated with HCV cure; to review the few safety issues linked to oral …

[HTML][HTML] New therapies for hepatitis C virus infection

JL Horsley-Silva, HE Vargas - Gastroenterology & hepatology, 2017 - ncbi.nlm.nih.gov
Approximately 350 million people worldwide are infected with hepatitis C virus (HCV), which
is associated with morbidity and mortality related to cirrhosis, hepatocellular carcinoma, or …