Astrocyte gliotransmission in the regulation of systemic metabolism
CDB Murat, C García-Cáceres - Metabolites, 2021 - mdpi.com
Normal brain function highly relies on the appropriate functioning of astrocytes. These glial
cells are strategically situated between blood vessels and neurons, provide significant …
cells are strategically situated between blood vessels and neurons, provide significant …
Brain metabolic sensing and metabolic signaling at the level of an astrocyte
Astrocytes support neuronal function by providing essential structural and nutritional
support, neurotransmitter trafficking and recycling and may also contribute to brain …
support, neurotransmitter trafficking and recycling and may also contribute to brain …
The astrocyte: metabolic hub of the brain
LF Barros, S Schirmeier… - Cold Spring Harbor …, 2024 - cshperspectives.cshlp.org
Astrocytic metabolism has taken center stage. Interposed between the neuron and the
vasculature, astrocytes exert control over the fluxes of energy and building blocks required …
vasculature, astrocytes exert control over the fluxes of energy and building blocks required …
Astrocyte-neuron metabolic cooperation shapes brain activity
G Bonvento, JP Bolaños - Cell metabolism, 2021 - cell.com
The brain has almost no energy reserve, but its activity coordinates organismal function, a
burden that requires precise coupling between neurotransmission and energy metabolism …
burden that requires precise coupling between neurotransmission and energy metabolism …
Physiological and pathophysiological roles of hypothalamic astrocytes in metabolism
JA Chowen, LM Frago… - Journal of …, 2019 - Wiley Online Library
The role of glial cells, including astrocytes, in metabolic control has received increasing
attention in recent years. Although the original interest in these macroglial cells was a result …
attention in recent years. Although the original interest in these macroglial cells was a result …
Glial cells as integrators of peripheral and central signals in the regulation of energy homeostasis
Communication between the periphery and the brain is key for maintaining energy
homeostasis. To do so, peripheral signals from the circulation reach the brain via the …
homeostasis. To do so, peripheral signals from the circulation reach the brain via the …
Role of astrocytes, microglia, and tanycytes in brain control of systemic metabolism
Astrocytes, microglia, and tanycytes play active roles in the regulation of hypothalamic
feeding circuits. These non-neuronal cells are crucial in determining the functional …
feeding circuits. These non-neuronal cells are crucial in determining the functional …
Astrocyte involvement in metabolic regulation and disease
Astrocytes, the predominant glial cell type in the mammalian brain, influence a wide variety
of brain parameters including neuronal energy metabolism. Exciting recent studies have …
of brain parameters including neuronal energy metabolism. Exciting recent studies have …
A role for astrocytes in the central control of metabolism
Over the last decades, the negative health consequences of obesity have triggered massive
searches for the cause of–and potential solutions for–the excessive mismatch between …
searches for the cause of–and potential solutions for–the excessive mismatch between …
The role of astrocytes in the hypothalamic response and adaptation to metabolic signals
JA Chowen, P Argente-Arizón, A Freire-Regatillo… - Progress in …, 2016 - Elsevier
The hypothalamus is crucial in the regulation of homeostatic functions in mammals, with the
disruption of hypothalamic circuits contributing to chronic conditions such as obesity …
disruption of hypothalamic circuits contributing to chronic conditions such as obesity …