Lupin seed hydrolysate promotes G-protein-coupled receptor, intracellular Ca2+ and enhanced glycolytic metabolism-mediated insulin secretion from BRIN-BD11 …
M Tapadia, R Carlessi, S Johnson, R Utikar… - Molecular and cellular …, 2019 - Elsevier
Lupin seed proteins have been reported to exhibit hypoglycaemic effects in animals and
humans following oral administration, however little is known about its mechanism of action …
humans following oral administration, however little is known about its mechanism of action …
Lupinus mutabilis Extract Exerts an Anti-Diabetic Effect by Improving Insulin Release in Type 2 Diabetic Goto-Kakizaki Rats
S Zambrana, LCE Lundqvist, O Mamani, SB Catrina… - Nutrients, 2018 - mdpi.com
Lupinus mutabilis (LM) is a legume part of Bolivian traditional diet that has a nutraceutical
property reducing blood glucose levels. The prevalence of type 2 diabetes is increasing …
property reducing blood glucose levels. The prevalence of type 2 diabetes is increasing …
Administration of Lupinus albus Gamma Conglutin (Cγ) to n5 STZ Rats Augmented Ins-1 Gene Expression and Pancreatic Insulin Content
B Vargas-Guerrero, PM García-López… - Plant foods for human …, 2014 - Springer
Several studies support the health-promoting benefits of lupins, particularly lupin proteins. It
has been demonstrated that Lupinus albus gamma conglutin (Cγ) protein lowered blood …
has been demonstrated that Lupinus albus gamma conglutin (Cγ) protein lowered blood …
Insulin-mimetic action of conglutin-γ, a lupin seed protein, in mouse myoblasts
I Terruzzi, P Senesi, C Magni, A Montesano… - Nutrition, Metabolism …, 2011 - Elsevier
BACKGROUND AND AIMS: Lupin seed is referred to as an antidiabetic product in traditional
medicine. Conglutin-γ, a lupin seed glycoprotein, was found to cause a significant plasma …
medicine. Conglutin-γ, a lupin seed glycoprotein, was found to cause a significant plasma …
[HTML][HTML] Antidiabetic effects and mechanisms of action of γ-conglutin from lupin seeds
M Tapadia, S Johnson, R Utikar, P Newsholme… - Journal of Functional …, 2021 - Elsevier
The glucose modulating properties of lupin have been attributed to its seed protein γ-
conglutin. Here we explored the antidiabetic potential of γ-conglutin purified from lupin …
conglutin. Here we explored the antidiabetic potential of γ-conglutin purified from lupin …
Insulinotropic action of white lupine seeds (Lupinus albus L.): effects on ion fluxes and insulin secretion from isolated pancreatic islets
FC Pereira, R Ouedraogo, P Lebrun… - Biomedical …, 2001 - jstage.jst.go.jp
Debittered seeds of Lupimzs afbus L. are generally considered to have antidiabetic
properties and are even prescribed by some physicians to counter hyperglycemia. We have …
properties and are even prescribed by some physicians to counter hyperglycemia. We have …
Lupanine Improves Glucose Homeostasis by Influencing KATP Channels and Insulin Gene Expression
M Wiedemann, CM Gurrola-Díaz, B Vargas-Guerrero… - Molecules, 2015 - mdpi.com
The glucose-lowering effects of lupin seeds involve the combined action of several
components. The present study investigates the influence of one of the main quinolizidine …
components. The present study investigates the influence of one of the main quinolizidine …
Urolithin C increases glucose‐induced ERK activation which contributes to insulin secretion
S Toubal, C Oiry, M Bayle, G Cros… - Fundamental & Clinical …, 2020 - Wiley Online Library
Polyphenols exert pharmacological actions through protein‐mediated mechanisms and by
modulating intracellular signalling pathways. We recently showed that a gut‐microbial …
modulating intracellular signalling pathways. We recently showed that a gut‐microbial …
Phytochemicals modulate pancreatic islet β cell function through glucagon-like peptide-1-related mechanisms
W Zheng, L Li, H Li - Biochemical Pharmacology, 2022 - Elsevier
Abstract Glucagon-like peptide-1 (GLP-1) receptor-based therapies have been developed
and extensively applied in clinical practice. GLP-1 plays an important role in improving …
and extensively applied in clinical practice. GLP-1 plays an important role in improving …
Insulin secretion effect of 2, 17-dioxosparteine, 17-thionosparteine, multiflorine and 17-hydroxy-lupanine on rat Langerhan's islets.
CM Gurrola-Díaz, MI Borelli, AK Przybyl… - 2008 - cabidigitallibrary.org
Some lupin species have been used as natural remedy for the treatment of diabetes. It has
been also demonstrated that lupin quinolizidine alkaloids (QAs) like multiflorine possess …
been also demonstrated that lupin quinolizidine alkaloids (QAs) like multiflorine possess …
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