Racial and Ethnic Differences in BRCA1/2 and Multigene Panel Testing Among Young Breast Cancer Patients

T Jones, MS Trivedi, X Jiang, T Silverman… - Journal of Cancer …, 2021 - Springer
Genetic testing for hereditary breast and ovarian cancer (HBOC) is recommended for breast
cancer patients diagnosed at age≤ 50 years. Our objective was to examine racial/ethnic …

Underdiagnosis of hereditary breast cancer: are genetic testing guidelines a tool or an obstacle?

PD Beitsch, PW Whitworth, K Hughes… - Journal of Clinical …, 2019 - ascopubs.org
Purpose An estimated 10% of breast and ovarian cancers result from hereditary causes.
Current testing guidelines for germ line susceptibility genes in patients with breast …

Germline genetic testing in breast cancer: rationale for the testing of all women diagnosed by the age of 60 years and for risk‐based testing of those older than 60 …

NV Desai, S Yadav, F Batalini, FJ Couch, NM Tung - Cancer, 2021 - Wiley Online Library
Approximately 5% to 10% of women diagnosed with breast cancer will have a pathogenic
variant (PV) in a hereditary cancer susceptibility gene, and this has significant implications …

Clinical actionability of multigene panel testing for hereditary breast and ovarian cancer risk assessment

A Desmond, AW Kurian, M Gabree, MA Mills… - JAMA …, 2015 - jamanetwork.com
Importance The practice of genetic testing for hereditary breast and/or ovarian cancer
(HBOC) is rapidly evolving owing to the recent introduction of multigene panels. While these …

Decision making about genetic testing among women with a personal and family history of breast cancer

D Scott, S Friedman, ML Telli, AW Kurian - JCO oncology practice, 2020 - ascopubs.org
PURPOSE: To understand genetic testing use and decision making among patients with
high genetic risk. MATERIALS AND METHODS: A survey of breast cancer survivors was …

National estimates of genetic testing in women with a history of breast or ovarian cancer

CP Childers, KK Childers… - Journal of Clinical …, 2017 - ascopubs.org
Purpose In the United States, 3.8 million women have a history of breast (BC) or ovarian
cancer (OC). Up to 15% of cases are attributable to heritable mutations, which, if identified …

[HTML][HTML] Genetic testing in young women with breast cancer: results from a Web-based survey

KJ Ruddy, S Gelber, J Shin, JE Garber, R Rosenberg… - Annals of …, 2010 - Elsevier
Background Young women with breast cancer have an increased risk for harboring a
BRCA1 or BRCA2 mutation. Frequency of genetic testing and factors associated with testing …

Influence of race/ethnicity on genetic counseling and testing for hereditary breast and ovarian cancer

AD Forman, MJ Hall - The breast journal, 2009 - Wiley Online Library
Risk assessment coupled with genetic counseling and testing for the cancer predisposition
genes BRCA1 and BRCA2 (BRCA1/2) has become an integral element of comprehensive …

Implementing a screening tool for identifying patients at risk for hereditary breast and ovarian cancer: a statewide initiative

L Brannon Traxler, ML Martin, AS Kerber… - Annals of surgical …, 2014 - Springer
Abstract Background The Georgia Breast Cancer Genomic Health Consortium is a
partnership created with funding from the Centers for Disease Control and Prevention (CDC) …

Factors associated with genetic counseling and BRCA testing in a population-based sample of young Black women with breast cancer

D Cragun, D Bonner, J Kim, MR Akbari… - Breast cancer research …, 2015 - Springer
Concerns about the potential for genomic advances to increase health disparities have been
raised. Thus, it is important to assess referral and uptake of genetic counseling (GC) and …