[HTML][HTML] Different DNA end configurations dictate which NHEJ components are most important for joining efficiency
HHY Chang, G Watanabe, CA Gerodimos… - Journal of Biological …, 2016 - ASBMB
The nonhomologous DNA end-joining (NHEJ) pathway is a key mechanism for repairing
dsDNA breaks that occur often in eukaryotic cells. In the simplest model, these breaks are …
dsDNA breaks that occur often in eukaryotic cells. In the simplest model, these breaks are …
Non‐homologous end joining: common interaction sites and exchange of multiple factors in the DNA repair process
Non‐homologous end‐joining (NHEJ) is the dominant means of repairing chromosomal
DNA double strand breaks (DSBs), and is essential in human cells. Fifteen or more proteins …
DNA double strand breaks (DSBs), and is essential in human cells. Fifteen or more proteins …
[HTML][HTML] Nonhomologous DNA end-joining for repair of DNA double-strand breaks
NR Pannunzio, G Watanabe, MR Lieber - Journal of Biological Chemistry, 2018 - ASBMB
Nonhomologous DNA end-joining (NHEJ) is the predominant double-strand break (DSB)
repair pathway throughout the cell cycle and accounts for nearly all DSB repair outside of …
repair pathway throughout the cell cycle and accounts for nearly all DSB repair outside of …
[PDF][PDF] A biochemically defined system for mammalian nonhomologous DNA end joining
Y Ma, H Lu, B Tippin, MF Goodman, N Shimazaki… - Molecular cell, 2004 - cell.com
Nonhomologous end joining (NHEJ) is a major pathway in multicellular eukaryotes for
repairing double-strand DNA breaks (DSBs). Here, the NHEJ reactions have been …
repairing double-strand DNA breaks (DSBs). Here, the NHEJ reactions have been …
Organization and dynamics of the nonhomologous end-joining machinery during DNA double-strand break repair
DA Reid, S Keegan, A Leo-Macias… - Proceedings of the …, 2015 - National Acad Sciences
Nonhomologous end-joining (NHEJ) is a major repair pathway for DNA double-strand
breaks (DSBs), involving synapsis and ligation of the broken strands. We describe the use of …
breaks (DSBs), involving synapsis and ligation of the broken strands. We describe the use of …
Nonhomologous end joining: new accessory factors fine tune the machinery
D Ghosh, SC Raghavan - Trends in Genetics, 2021 - cell.com
Nonhomologous DNA end joining (NHEJ) is one of the major DNA double-strand break
(DSB) repair pathways in eukaryotes. The well-known critical proteins involved in NHEJ …
(DSB) repair pathways in eukaryotes. The well-known critical proteins involved in NHEJ …
Defining interactions between DNA-PK and ligase IV/XRCC4
HL Hsu, SM Yannone, DJ Chen - DNA repair, 2002 - Elsevier
Non-homologous end joining (NHEJ) is a major pathway for the repair of DNA double-strand
breaks (DSBs) in mammalian cells. DNA-dependent protein kinase (DNA-PK), ligase IV, and …
breaks (DSBs) in mammalian cells. DNA-dependent protein kinase (DNA-PK), ligase IV, and …
Xrcc4 physically links DNA end processing by polynucleotide kinase to DNA ligation by DNA ligase IV
CA Koch, R Agyei, S Galicia, P Metalnikov… - The EMBO …, 2004 - embopress.org
Nonhomologous end joining (NHEJ) is the major DNA double‐strand break (DSB) repair
pathway in mammalian cells. A critical step in this process is DNA ligation, involving the …
pathway in mammalian cells. A critical step in this process is DNA ligation, involving the …
Identification of DNA-PKcs phosphorylation sites in XRCC4 and effects of mutations at these sites on DNA end joining in a cell-free system
KJ Lee, M Jovanovic, D Udayakumar, CL Bladen… - DNA repair, 2004 - Elsevier
Nonhomologous end joining (NHEJ) is the principal mechanism for repairing DNA double-
strand breaks in mammalian cells. NHEJ requires at least three protein components: the …
strand breaks in mammalian cells. NHEJ requires at least three protein components: the …
The Ku80 carboxy terminus stimulates joining and artemis-mediated processing of DNA ends
E Weterings, NS Verkaik, G Keijzers… - … and cellular biology, 2009 - Taylor & Francis
Repair of DNA double-strand breaks (DSBs) is predominantly mediated by nonhomologous
end joining (NHEJ) in mammalian cells. NHEJ requires binding of the Ku70-Ku80 …
end joining (NHEJ) in mammalian cells. NHEJ requires binding of the Ku70-Ku80 …