[HTML][HTML] Curcumin decreases malignant characteristics of glioblastoma stem cells via induction of reactive oxygen species

ZC Gersey, GA Rodriguez, E Barbarite, A Sanchez… - BMC cancer, 2017 - Springer
Abstract Background Glioblastoma Multiforme (GBM) is the most common and lethal form of
primary brain tumor in adults. Following standard treatment of surgery, radiation and …

[HTML][HTML] The nontoxic natural compound Curcumin exerts anti-proliferative, anti-migratory, and anti-invasive properties against malignant gliomas

C Senft, M Polacin, M Priester, V Seifert, D Kögel… - BMC cancer, 2010 - Springer
Background New drugs are constantly sought after to improve the survival of patients with
malignant gliomas. The ideal substance would selectively target tumor cells without eliciting …

Therapeutic potential of curcumin in the treatment of glioblastoma multiforme

SH Shahcheraghi, M Zangui, M Lotfi… - Current …, 2019 - ingentaconnect.com
Glioblastoma multiforme (GBM) is the most common primary malignant brain tumor. Despite
standard multimodality treatment, the highly aggressive nature of GBM makes it one of the …

Review on the therapeutic potential of curcumin and its derivatives on glioma biology

M Mohamadian, SS Ahmadi, A Bahrami… - Neurochemical …, 2022 - Springer
Gliomas are common and aggressive brain tumors that carry a poor prognosis. The current
multimodal therapeutic option for glioma includes surgery subsequently temozolomide …

A polymeric nanoparticle formulation of curcumin inhibits growth, clonogenicity and stem-like fraction in malignant brain tumors

KJ Lim, S Bisht, EE Bar, A Maitra… - Cancer biology & …, 2011 - Taylor & Francis
Curcumin is a polyphenolic compound derived from the Indian spice turmeric. We used
nanoparticle-encapsulated curcumin to treat medulloblastoma and glioblastoma cells. This …

[HTML][HTML] Anticancer mechanism of curcumin on human glioblastoma

SC Wong, MNA Kamarudin, R Naidu - Nutrients, 2021 - mdpi.com
Glioblastoma (GBM) is the most malignant brain tumor and accounts for most adult brain
tumors. Current available treatment options for GBM are multimodal, which include surgical …

The curry spice curcumin selectively inhibits cancer cells growth in vitro and in preclinical model of glioblastoma

A Zanotto-Filho, E Braganhol, MI Edelweiss… - The Journal of nutritional …, 2012 - Elsevier
Previous studies suggested that curcumin is a potential agent against glioblastomas
(GBMs). However, the in vivo efficacy of curcumin in gliomas remains not established. In this …

[HTML][HTML] Combination treatment of berberine and solid lipid curcumin particles increased cell death and inhibited PI3K/Akt/mTOR pathway of human cultured …

P Maiti, A Plemmons, GL Dunbar - PloS one, 2019 - journals.plos.org
The treatment of glioblastoma is challenging for the clinician, due to its chemotherapeutic
resistance. Recent findings suggest that targeting glioblastoma using anti-cancer natural …

Curcumin promotes differentiation of glioma‐initiating cells by inducing autophagy

W Zhuang, L Long, B Zheng, W Ji, N Yang… - Cancer …, 2012 - Wiley Online Library
Glioblastoma (GBM) is a highly aggressive brain tumor characterized by increased
proliferation and resistance to chemotherapy and radiotherapy. Recently, a growing body of …

Therapeutic potential of curcumin for the treatment of brain tumors

NV Klinger, S Mittal - Oxidative medicine and cellular longevity, 2016 - Wiley Online Library
Brain malignancies currently carry a poor prognosis despite the current multimodal standard
of care that includes surgical resection and adjuvant chemotherapy and radiation. As new …