[HTML][HTML] Protein-induced fusion can be modulated by target membrane lipids through a structural switch at the level of the fusion peptide

EI Pécheur, I Martin, A Bienvenüe… - Journal of Biological …, 2000 - ASBMB
Regulatory features of protein-induced membrane fusion are largely unclear, particularly at
the level of the fusion peptide. Fusion peptides being part of larger protein complexes, such …

[HTML][HTML] Oligomerization of fusogenic peptides promotes membrane fusion by enhancing membrane destabilization

WL Lau, DS Ege, JD Lear, DA Hammer, WF Degrado - Biophysical journal, 2004 - cell.com
A key element of membrane fusion reactions in biology is the involvement of specific fusion
proteins. In many viruses, the proteins that mediate membrane fusion usually exist as …

Lipid headgroup spacing and peptide penetration, but not peptide oligomerization, modulate peptide-induced fusion

EI Pécheur, J Sainte-Marie, A Bienvenüe… - Biochemistry, 1999 - ACS Publications
In this study, the mechanism by which an amphipathic negatively charged peptide consisting
of 11 amino acids (WAE) induces fusion of liposomal phosphatidylcholine membranes is …

Molecular view of the role of fusion peptides in promoting positive membrane curvature

M Fuhrmans, SJ Marrink - Journal of the American Chemical …, 2012 - ACS Publications
Fusion peptides are moderately hydrophobic segments of viral and nonviral membrane
fusion proteins that enable these proteins to fuse two closely apposed biological …

[HTML][HTML] Membrane composition modulates fusion by altering membrane properties and fusion peptide structure

G Meher, H Chakraborty - The Journal of membrane biology, 2019 - Springer
Membrane fusion, one of the most essential processes in the life of eukaryotes, occurs when
two separate lipid bilayers merge into a continuous bilayer and internal contents of two …

[HTML][HTML] Hemagglutinin fusion peptide mutants in model membranes: structural properties, membrane physical properties, and PEG-mediated fusion

ME Haque, H Chakraborty, T Koklic, H Komatsu… - Biophysical journal, 2011 - cell.com
While the importance of viral fusion peptides (eg, hemagglutinin (HA) and gp41) in virus-cell
membrane fusion is established, it is unclear how these peptides enhance membrane …

[HTML][HTML] Plasticity and conformational equilibria of influenza fusion peptides in model lipid bilayers

NR Haria, L Monticelli, F Fraternali… - Biochimica et Biophysica …, 2014 - Elsevier
Membrane fusion is critical to eukaryotic cellular function and crucial to the entry of
enveloped viruses such as influenza and human immunodeficiency virus. Influenza viral …

Common properties of fusion peptides from diverse systems

I Martin, JM Ruysschaert - Bioscience reports, 2000 - portlandpress.com
Although membrane fusion occurs ubiquitously and continuously in alleukaroytic cells, little
is known about the mechanism that governs lipidbilayer fusion associated with any …

pH-dependence of intermediate steps of membrane fusion induced by the influenza fusion peptide

DK Chang, SF Cheng - Biochemical Journal, 2006 - portlandpress.com
Membrane fusion mediated by the influenza-virus fusion protein is activated by low pH via a
cascade of reactions. Some processes among them are irreversible, such as helix hairpin …

[HTML][HTML] Two modes of fusogenic action for influenza virus fusion peptide

M Michalski, P Setny - PLOS Computational Biology, 2023 - journals.plos.org
The entry of influenza virus into the host cell requires fusion of its lipid envelope with the host
membrane. It is catalysed by viral hemagglutinin protein, whose fragments called fusion …