PURPOSE OF REVIEW Although sporadic primary neoplasms account for the majority of
nervous system tumors, familial nervous system tumor syndromes are important and …

Tumors of the nervous system typically occur in a sporadic fashion without a pre-existing
familial predisposition. The uncommon tumors that arise in the context of a tumor …

The 3 most frequently encountered familial neoplastic syndromes that affect the central
and/or peripheral nervous systems include neurofibromatosis type I (NF-1) …

Neurofibromatosis Type 1 427 Neurofibromatosis Type 2 432 Schwannomatosis 435
Tuberous Sclerosis Complex 436 Von Hippel-Lindau Disease 439 Turcot Syndrome 443 …

Several familial syndromes are associated with an increased incidence of nervous system
tumors. Recognition of these syndromes is critical to provide optimal clinical care and …

The majority of tumors of the nervous system are sporadic. However, a subset of patients
with tumors and their families are predisposed to developing cancers of the central nervous …

Historically, clinicians made observations in their clinical practice regarding certain
associations of specific central nervous system (CNS) tumors and other clinical findings …

There are several genetic syndromes that predispose to the development of tumors of the
nervous system. In the present study, we provide a review of the tumors that are associated …

Hereditary central nervous tumor syndromes are a varied group of conditions that include
neurofibromatosis type 1 and 2, tuberous sclerosis, Von Hippel-Lindau disease, and …

Hereditary tumor syndromes of the nervous system are a varied group of conditions that
include neurofibromatosis 1, neurofibromatosis 2, tuberous sclerosis, and von Hippel …