Engineering of hybrid anticancer drug-loaded polymeric nanoparticles delivery system for the treatment and care of lung cancer therapy

Y Zhao, K Liu, J Li, J Liao, L Ma - Drug Delivery, 2021 - Taylor & Francis
Chemotherapy with combination drugs has become one of the most commonly used cancer
prevention treatments, with positive clinical results. The goal of this study was to develop …

Development and investigation of dual potent anticancer drug-loaded nanoparticles for the treatment of lung cancer therapy

N Zhou, W Wang, H Li, D Jiang, X Zhong - Process Biochemistry, 2021 - Elsevier
Combinations of two potent chemotherapeutic drugs are often used to treat early stage lung
cancer. To enhance the efficiency of the treatment, a combinational co-drug delivery system …

Co-loading of cisplatin and methotrexate in nanoparticle-based PCL-PEG system enhances lung cancer chemotherapy effects

E Akbari, H Mousazadeh, Y Hanifehpour… - Journal of Cluster …, 2022 - Springer
Since the anticancer drugs exhibited a variety of inhibitory mechanisms in cancer cells, the
use of two or more anticancer drugs may have excellent therapeutic effects, particularly in …

Polymeric nanoparticles as carrier for targeted and controlled delivery of anticancer agents

V Taghipour-Sabzevar, T Sharifi… - Therapeutic …, 2019 - Taylor & Francis
In recent decades, many novel methods by using nanoparticles (NPs) have been
investigated for diagnosis, drug delivery and treatment of cancer. Accordingly, the potential …

Preparation and characterization of PLGA-PEG-PLGA polymeric nanoparticles for co-delivery of 5-Fluorouracil and Chrysin

S Khaledi, S Jafari, S Hamidi, O Molavi… - Journal of Biomaterials …, 2020 - Taylor & Francis
Despite significant advances in cancer therapy, chemotherapeutic agents are still the main
types of drugs used to treat cancer patients. 5-Fluorouracil (5-FU) is the first-line treatment in …

Lung cancer combination treatment: evaluation of the synergistic effect of cisplatin prodrug, vinorelbine and retinoic acid when co-encapsulated in a multi-layered …

Z Liang, J Li, B Zhu - Drug Design, Development and Therapy, 2020 - Taylor & Francis
Purpose Lung cancer remains the leading cancer-associated deaths worldwide. Cisplatin
(CIS) was often used in combination with other drugs for the treatment of non-small cell lung …

Dual polymeric prodrug co-assembled nanoparticles with precise ratiometric co-delivery of cisplatin and metformin for lung cancer chemoimmunotherapy

T Yang, S Yu, L Liu, Y Sun, Y Lan, X Ma, R Zhu… - Biomaterials …, 2020 - pubs.rsc.org
The combination therapy of cisplatin (CDDP) and metformin (MET) is a clinical strategy to
enhance therapeutic outcomes in lung cancer. However, the efficacy of this combination is …

Disulfiram-loaded porous PLGA microparticle for inhibiting the proliferation and migration of non-small-cell lung cancer

C Wang, J Yang, H Han, J Chen, Y Wang… - International journal …, 2017 - Taylor & Francis
In this study, poly (lactic-co-glycolic acid)(PLGA) was used as a carrier to construct disulfiram-
loaded porous microparticle through the emulsion solvent evaporation method, using …

Precise engineering of hybrid molecules-loaded macromolecular nanoparticles shows in vitro and in vivo antitumor efficacy toward the treatment of nasopharyngeal …

D Liu, W Zhang, X Liu, R Qiu - Drug Delivery, 2021 - Taylor & Francis
Cancers continue to be the second leading cause of death worldwide. Despite the
development and improvement of surgery, chemotherapy, and radiotherapy in cancer …

Fabrication of gemcitabine and losmapimod-prodrug loaded nanoparticles for the treatment and care of lung cancer

R Zhao, J Qi - Materials Research Express, 2022 - iopscience.iop.org
Lung carcinoma (LC) is rare cancer in most parts of the world but is common cancer in
southern Asia. Local recurrent disease and distant metastasis of LC are still mysterious …