Therapeutic and Translational Applications of Extra-Virgin Olive Oil Phenolics

MH Qusa - 2021 - search.proquest.com
Natural products are chemically diverse structures with documented biological activity. The
diverse and renewable nature of the primary and secondary natural metabolites maintain …

[HTML][HTML] Principal Bioactive Properties of Oleanolic Acid, Its Derivatives, and Analogues

F Jannus, J Sainz, FJ Reyes-Zurita - Molecules, 2024 - mdpi.com
Natural products have always played an important role in pharmacotherapy, helping to
control pathophysiological processes associated with human disease. Thus, natural …

Pharmacokinetics and Metabolism Investigation of Oleocanthal

T Nikou, KV Karampetsou, OS Koutsoni… - Journal of Natural …, 2023 - ACS Publications
Oleocanthal is a secoiridoid found in olive oil, which lately gained great scientific interest
due to its important pharmacological spectrum and biological properties. However, limited …

Oleocanthal, a natural anti-inflammatory compound in extra virgin olive oil

S Cicerale, R SJ Keast - … -Inflammatory & Anti-Allergy Agents in …, 2010 - ingentaconnect.com
Recent research on the olive oil phenolic oleocanthal has led to speculation that it may
confer some of the health benefits associated with a traditional Mediterranean diet …

Short Lecture “New insights into the mechanism of action and bioavailability of oleocanthal and oleacein from olive oil”

F Kalyva, P Diamantakos, E Melliou… - Planta …, 2022 - thieme-connect.com
Oleocanthal (OC) and oleacein (OL) are highly bioactive secoiridoids found in olive oil at
elevated concentrations, especially when it is produced from unripe olives (Olea europaea …

Oleocanthalic acid, a chemical marker of olive oil aging and exposure to a high storage temperature with potential neuroprotective activity

A Tsolakou, P Diamantakos, I Kalaboki… - Journal of agricultural …, 2018 - ACS Publications
The investigation of olive oils stored for a period of 24 months under appropriate conditions
(25° C, dark place, and airtight container) led to the identification of a new major phenolic …

Oleocanthal exerts antitumor effects on human liver and colon cancer cells through ROS generation

A Cusimano, D Balasus… - International …, 2017 - spandidos-publications.com
The beneficial health properties of the Mediterranean diet are well recognized. The principle
source of fat in Mediterranean diet is extra-virgin olive oil (EVOO). Oleocanthal (OC) is a …

Oleanolic acid and its derivatives: biological activities and therapeutic potential in chronic diseases

TB Ayeleso, MG Matumba, E Mukwevho - Molecules, 2017 - mdpi.com
The increasing demand for natural products as an alternative therapy for chronic diseases
has encouraged research into the pharmacological importance of bioactive compounds from …

Oleanolic acid: extraction, characterization and biological activity

JM Castellano, S Ramos-Romero, JS Perona - Nutrients, 2022 - mdpi.com
Oleanolic acid, a pentacyclic triterpenoid ubiquitously present in the plant kingdom, is
receiving outstanding attention from the scientific community due to its biological activity …

A review on recent developments in the anticancer potential of oleanolic acid and its analogs (2017-2020)

N Gupta - Mini Reviews in Medicinal Chemistry, 2022 - ingentaconnect.com
Oleanolic acid (OA) is a pentacyclic triterpenoid class of natural products that possess a
broad range of biological activities, specifically anticancer activities. Considering the …