ACE2 and COVID-19 and the resulting ARDS

X Zhang, S Li, S Niu - Postgraduate medical journal, 2020 - academic.oup.com
This article reviews the correlation between ACE2 and COVID-19 and the resulting acute
respiratory distress syndrome (ARDS). ACE2 is a crucial component of the renin-angiotensin …

In silico studies on the comparative characterization of the interactions of SARS‐CoV‐2 spike glycoprotein with ACE‐2 receptor homologs and human TLRs

A Choudhury, S Mukherjee - Journal of medical virology, 2020 - Wiley Online Library
Abstract Coronavirus disease‐2019 (COVID‐19) outbreak due to novel coronavirus or
severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) infection has come out as …

In silico identification of Tretinoin as a SARS-CoV-2 envelope (E) protein ion channel inhibitor

D Dey, S Borkotoky, M Banerjee - Computers in biology and medicine, 2020 - Elsevier
Viroporins are oligomeric, pore forming, viral proteins that play critical roles in the life cycle
of pathogenic viruses. Viroporins like HIV-1 Vpu, Alphavirus 6 K, Influenza M2, HCV p7, and …

[HTML][HTML] Possible use of the mucolytic drug, bromhexine hydrochloride, as a prophylactic agent against SARS-CoV-2 infection based on its action on the …

S Habtemariam, SF Nabavi, S Ghavami… - Pharmacological …, 2020 - ncbi.nlm.nih.gov
As with all new virus diseases with no drug therapy, identifying key pharmacological targets
for SARS-coronavirus 2 (SARS-CoV-2 or 2019-nCoV) based on our knowledge of the viral …

Role of host factors in SARS-CoV-2 entry

JP Evans, SL Liu - Journal of Biological Chemistry, 2021 - ASBMB
The zoonotic transmission of highly pathogenic coronaviruses into the human population is
a pressing concern highlighted by the ongoing SARS-CoV-2 pandemic. Recent work has …

The role of cell death in SARS-CoV-2 infection

C Yuan, Z Ma, J Xie, W Li, L Su, G Zhang, J Xu… - … and Targeted Therapy, 2023 - nature.com
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), showing high
infectiousness, resulted in an ongoing pandemic termed coronavirus disease 2019 (COVID …

Inflammation triggered by SARS-CoV-2 and ACE2 augment drives multiple organ failure of severe COVID-19: molecular mechanisms and implications

M Iwasaki, J Saito, H Zhao, A Sakamoto, K Hirota, D Ma - Inflammation, 2021 - Springer
The widespread occurrence of severe acute respiratory syndrome coronavirus 2 (SARS-
CoV-2) has led to a pandemic of coronavirus disease 2019 (COVID-19). The S spike protein …

Pathophysiology of infection with SARS‐CoV‐2—What is known and what remains a mystery

S Sridhar, J Nicholls - Respirology, 2021 - Wiley Online Library
Abstract Coronavirus disease 2019 (COVID‐19), caused by coronavirus severe acute
respiratory syndrome coronavirus 2 (SARS‐CoV‐2), has caused extensive disruption and …

[HTML][HTML] Structure analysis of the receptor binding of 2019-nCoV

Y Chen, Y Guo, Y Pan, ZJ Zhao - Biochemical and biophysical research …, 2020 - Elsevier
nCoV is a newly identified coronavirus with high similarity to SARS-CoV. We performed a
structural analysis of the receptor binding domain (RBD) of spike glycoprotein responsible …

Potential role of ACE2 in coronavirus disease 2019 (COVID-19) prevention and management

M Liu, T Wang, Y Zhou, Y Zhao, Y Zhang… - Journal of translational …, 2020 - degruyter.com
COVID-19 is the current public health threat all over the world. Unfortunately, there is no
specific prevention and treatment strategy for this disease. We aim to explore the potential …