Tractography-pathology correlations in traumatic brain injury: a TRACK-TBI study

AL Nolan, C Petersen, D Iacono… - Journal of …, 2021 - liebertpub.com
Diffusion tractography magnetic resonance imaging (MRI) can infer changes in network
connectivity in patients with traumatic brain injury (TBI), but the pathological substrates of …

[HTML][HTML] Automated detection of axonal damage along white matter tracts in acute severe traumatic brain injury

C Maffei, N Gilmore, SB Snider, AS Foulkes… - NeuroImage: Clinical, 2023 - Elsevier
New techniques for individualized assessment of white matter integrity are needed to detect
traumatic axonal injury (TAI) and predict outcomes in critically ill patients with acute severe …

White matter tract integrity: an indicator of axonal pathology after mild traumatic brain injury

S Chung, E Fieremans, X Wang… - Journal of …, 2018 - liebertpub.com
We seek to elucidate the underlying pathophysiology of injury sustained after mild traumatic
brain injury (mTBI) using multi-shell diffusion magnetic resonance imaging, deriving …

Quantifying white matter structural integrity with high-definition fiber tracking in traumatic brain injury

N Presson, D Krishnaswamy, L Wagener… - Military …, 2015 - academic.oup.com
There is an urgent, unmet demand for definitive biological diagnosis of traumatic brain injury
(TBI) to pinpoint the location and extent of damage. We have developed High-Definition …

Statistical machine learning to identify traumatic brain injury (TBI) from structural disconnections of white matter networks

J Mitra, K Shen, S Ghose, P Bourgeat, J Fripp… - Neuroimage, 2016 - Elsevier
Identifying diffuse axonal injury (DAI) in patients with traumatic brain injury (TBI) presenting
with normal appearing radiological MRI presents a significant challenge. Neuroimaging …

Assessing connectivity related injury burden in diffuse traumatic brain injury

B Solmaz, B Tunç, D Parker, J Whyte… - Human brain …, 2017 - Wiley Online Library
Many of the clinical and behavioral manifestations of traumatic brain injury (TBI) are thought
to arise from disruption to the structural network of the brain due to diffuse axonal injury …

MRI-based measures of intracortical myelin are sensitive to a history of TBI and are associated with functional connectivity

EM Gordon, GJ May, SM Nelson - NeuroImage, 2019 - Elsevier
Traumatic brain injuries (TBIs) induce persistent behavioral and cognitive deficits via diffuse
axonal injury. Axonal injuries are often examined in vivo using diffusion MRI, which identifies …

[HTML][HTML] A robust method for investigating thalamic white matter tracts after traumatic brain injury

L Squarcina, A Bertoldo, TE Ham, R Heckemann… - Neuroimage, 2012 - Elsevier
Damage to the structural connections of the thalamus is a frequent feature of traumatic brain
injury (TBI) and can be a key factor in determining clinical outcome. Until recently it has been …

Detection of traumatic axonal injury with diffusion tensor imaging in a mouse model of traumatic brain injury

CL Mac Donald, K Dikranian, SK Song, PV Bayly… - Experimental …, 2007 - Elsevier
Traumatic axonal injury (TAI) is thought to be a major contributor to cognitive dysfunction
following traumatic brain injury (TBI), however TAI is difficult to diagnose or characterize non …

Differential tractography as a track-based biomarker for neuronal injury

FC Yeh, IM Zaydan, VR Suski, D Lacomis… - Neuroimage, 2019 - Elsevier
Diffusion MRI tractography has been used to map the axonal structure of the human brain,
but its ability to detect neuronal injury is yet to be explored. Here we report differential …