The Role and Therapeutic Implications of Inflammation in the Pathogenesis of Brain Arteriovenous Malformations
Brain arteriovenous malformations (bAVMs) are focal vascular lesions composed of
abnormal vascular channels without an intervening capillary network. As a result, high …
abnormal vascular channels without an intervening capillary network. As a result, high …
Neurovascular inflammation in the pathogenesis of brain arteriovenous malformations
S Krithika, S Sumi - Journal of Cellular Physiology, 2021 - Wiley Online Library
Brain arteriovenous malformations (bAVM) arise as congenital or sporadic focal lesions with
a significant risk for intracerebral hemorrhage (ICH). A wide range of interindividual …
a significant risk for intracerebral hemorrhage (ICH). A wide range of interindividual …
[图书][B] Vascular integrity in the pathogenesis of brain arteriovenous malformation
Brain arteriovenous malformation (bAVM) is an important cause of intracranial hemorrhage
(ICH), particularly in the young population. ICH is the first clinical symptom in about 50% of …
(ICH), particularly in the young population. ICH is the first clinical symptom in about 50% of …
Biology of cerebral arteriovenous malformations with a focus on inflammation
N Mouchtouris, PM Jabbour… - Journal of Cerebral …, 2015 - journals.sagepub.com
Cerebral arteriovenous malformations (AVMs) entail a significant risk of intracerebral
hemorrhage owing to the direct shunting of arterial blood into the venous vasculature …
hemorrhage owing to the direct shunting of arterial blood into the venous vasculature …
Current concepts and perspectives on brain arteriovenous malformations: a review of pathogenesis and multidisciplinary treatment
Brain arteriovenous malformations (bAVMs) are unusual vascular pathologies characterized
by the abnormal aggregation of dilated arteries and veins in the brain parenchyma and for …
by the abnormal aggregation of dilated arteries and veins in the brain parenchyma and for …
Persistent infiltration and pro-inflammatory differentiation of monocytes cause unresolved inflammation in brain arteriovenous malformation
R Zhang, Z Han, V Degos, F Shen, EJ Choi, Z Sun… - Angiogenesis, 2016 - Springer
An abnormally high number of macrophages are present in human brain arteriovenous
malformations (bAVM) with or without evidence of prior hemorrhage, causing unresolved …
malformations (bAVM) with or without evidence of prior hemorrhage, causing unresolved …
CNS resident macrophages enhance dysfunctional angiogenesis and circulating monocytes infiltration in brain arteriovenous malformation
Myeloid immune cells are abundant in both ruptured and unruptured brain arteriovenous
malformations (bAVMs). The role of central nervous system (CNS) resident and circulating …
malformations (bAVMs). The role of central nervous system (CNS) resident and circulating …
Defective vascular signaling & prospective therapeutic targets in brain arteriovenous malformations
The neurovascular unit is composed of endothelial cells, vascular smooth muscle cells,
pericytes, astrocytes and neurons. Through tightly regulated multi-directional cell signaling …
pericytes, astrocytes and neurons. Through tightly regulated multi-directional cell signaling …
[HTML][HTML] Cellular loci involved in the development of brain arteriovenous malformations
Brain arteriovenous malformations (bAVMs) are abnormal vessels that are prone to rupture,
causing life-threatening intracranial bleeding. The mechanism of bAVM formation is not fully …
causing life-threatening intracranial bleeding. The mechanism of bAVM formation is not fully …
[HTML][HTML] The role of macrophage in the pathogenesis of brain arteriovenous malformation
Brain arteriovenous malformation (BAVM) is an important risk factor for intracranial
hemorrhage, especially in children and young adults. Inflammation has been implicated in …
hemorrhage, especially in children and young adults. Inflammation has been implicated in …