Abuse and misuse of second‐generation antipsychotics: an analysis using VigiBase, the World Health Organisation pharmacovigilance database

S Roy, R Charreteur, M Peries… - British journal of …, 2022 - Wiley Online Library
The study aim was to assess the abuse/misuse potential of second‐generation
antipsychotics (SGAPs) using VigiBase data. We extracted individual case safety reports of …

Is there a potential of misuse for quetiapine?: Literature review and analysis of the European Medicines Agency/European Medicines Agency Adverse Drug Reactions' …

S Chiappini, F Schifano - Journal of Clinical Psychopharmacology, 2018 - journals.lww.com
Purpose/Background A recent years' increase in both prescribing and availability of second-
generation antipsychotics (SGAs) has been observed. According to the literature, typically …

Comparison of quetiapine abuse and misuse reports to the FDA Adverse Event Reporting System with other second-generation antipsychotics

KE Evoy, C Teng, VG Encarnacion… - Substance Abuse …, 2019 - journals.sagepub.com
Background: Second-generation antipsychotics (SGAs) are assumed to have little abuse
potential. However, reports of quetiapine abuse have emerged as prescribing has increased …

Characteristics of voluntary reporting of adverse drug events related to antipsychotics in Australia: 14-year analysis

H Khalil, D Hoppe, N Ameen - Therapeutic Advances in Drug …, 2021 - journals.sagepub.com
Background: Retrospective analyses of large databases of treated patients can provide
useful links to the presence of drug misuse or rare and infrequent adverse effects, such as …

Patterns of suboptimal antipsychotic use and misuse in Australia: What can routinely collected data tell us?

J Brett, MB Gillies, NA Buckley… - British Journal of …, 2023 - Wiley Online Library
Aims There are increasing concerns about harms related to suboptimal antipsychotic use.
Here we describe recent population‐based trends in antipsychotic use and harms in …

Comparative safety of antipsychotics in the WHO pharmacovigilance database: the haloperidol case

C Meyer-Massetti, S Vaerini, AE Rätz Bravo… - International journal of …, 2011 - Springer
Background Starting in 2007, regulatory agencies strengthened label warnings for
intravenous haloperidol. Based on adverse drug reaction (ADR) reports of QT prolongation …

Pharmaco-epidemiology: what do (and don't) we know about utilisation and impact of psychotropic medications in real-life conditions?

H Verdoux, B Bégaud - The British Journal of Psychiatry, 2004 - cambridge.org
VERDOUX & BEGAUD VERDOUX & BE¤ GAUD have a serious impact on the health of the
population if many people are exposed to the drug. Surveillance by centralised pooling of …

Antipsychotic-Related Fatal Poisoning, England and Wales, 1993–2019: The Impact of Second-Generation Antipsychotics

SA Handley, S Every-Palmer… - Journal of clinical …, 2021 - journals.lww.com
Background Deaths from antipsychotic (AP) poisoning have increased in England and
Wales despite restriction of the use of thioridazine in 2000. Methods We analyzed data from …

[HTML][HTML] Torsadogenic risk of antipsychotics: combining adverse event reports with drug utilization data across Europe

E Raschi, E Poluzzi, B Godman, A Koci, U Moretti… - PLoS …, 2013 - journals.plos.org
Background Antipsychotics (APs) have been associated with risk of torsade de Pointes
(TdP). This has important public health implications. Therefore,(a) we exploited the public …

[HTML][HTML] Comparative safety signal assessment of hospitalization associated with the use of atypical antipsychotics

I Yunusa, C Teng, IM Karaye, E Crounse… - Frontiers in …, 2022 - frontiersin.org
Background Persons with symptoms of psychosis receiving treatment with atypical
antipsychotics (AAPs) can experience serious adverse events (AEs) requiring admission to …