Background The biomechanical properties of the lung are necessarily dependent on its
structure and function, both of which are complex and change over time and space. This …

The mechanics of breathing is a fascinating and vital process. The lung has complexities
and subtle heterogeneities in structure across length scales that influence mechanics and …

Lungs represent the essential part of the mammalian respiratory system, which is reflected in
the fact that lung failure still is one of the leading causes of morbidity and mortality …

Multiple thoracic imaging modalities have been developed to link structure to function in the
diagnosis and monitoring of lung disease. Volumetric computed tomography (CT) renders …

Spirometry is today the gold standard technique for assessing pulmonary ventilatory function
in humans. From the shape of a flow-volume loop measured while the patient is performing …

This review provides a summary of pulmonary functional imaging approaches for
determining pulmonary ventilation, with a specific focus on multi-detector x-ray computed …

Due to the close interaction of lung morphology and functions, repeatable measurements of
pulmonary function during longitudinal studies on lung pathophysiology and treatment …

Dynamic heterogeneity in lung ventilation is an important measure of pulmonary function
and may be characteristic of early pulmonary disease. While standard indices like …

The study of lung mechanics is important to futureproof resilience against potential novel
threats to lung health. Medical imaging provides insight to lung function. High-resolution …

Noninvasive image‐based measurement of intrinsic tissue pressure is of great interest in the
diagnosis and characterization of diseases. Therefore, we propose to exploit the capability …