The natural plant flavonoid apigenin is a strong antioxidant that effectively delays peripheral neurodegenerative processes
M Kim, J Jung, NY Jeong, HJ Chung - Anatomical Science International, 2019 - Springer
Oxidative stress contributes to the progression of neurodegenerative diseases of the central
and peripheral nervous systems, including Alzheimer's disease, Parkinson's disease, stroke …
and peripheral nervous systems, including Alzheimer's disease, Parkinson's disease, stroke …
The flavonoid apigenin protects brain neurovascular coupling against amyloid-β 25-35-induced toxicity in mice
R Liu, T Zhang, H Yang, X Lan… - Journal of Alzheimer's …, 2011 - content.iospress.com
Apigenin, one of the most common flavonoids, has demonstrated anti-inflammatory,
anticarcinogenic, and free radical-scavenging activities. Recent studies revealed its …
anticarcinogenic, and free radical-scavenging activities. Recent studies revealed its …
Anti-inflammatory and neuroprotective effect of apigenin: studies in the GFAP-IL6 mouse model of chronic neuroinflammation
Background Chronic neuroinflammation (activation of microglia and astrocytes) is a
prominent pathological process in many neurodegenerative diseases including Alzheimer's …
prominent pathological process in many neurodegenerative diseases including Alzheimer's …
Potential role of flavonoids in treating chronic inflammatory diseases with a special focus on the anti-inflammatory activity of apigenin
Inflammation has been reported to be intimately linked to the development or worsening of
several non-infectious diseases. A number of chronic conditions such as cancer, diabetes …
several non-infectious diseases. A number of chronic conditions such as cancer, diabetes …
Functionality of apigenin as a potent antioxidant with emphasis on bioavailability, metabolism, action mechanism and in vitro and in vivo studies: A review
Numerous diseases such as cancer, diabetes, cardiovascular, neurodegenerative diseases,
etc. are linked with overproduction of reactive oxygen species (ROS) and oxidative stress …
etc. are linked with overproduction of reactive oxygen species (ROS) and oxidative stress …
[HTML][HTML] Polyphenolic antioxidants and neuronal regeneration
A Ataie, M Shadifar, R Ataee - Basic and Clinical Neuroscience, 2016 - ncbi.nlm.nih.gov
Many studies indicate that oxidative stress is involved in the pathophysiology of
neurodegenerative diseases. Oxidative stress can induce neuronal damages, modulate …
neurodegenerative diseases. Oxidative stress can induce neuronal damages, modulate …
[HTML][HTML] Neuroimmunomodulatory and Neuroprotective Effects of the Flavonoid Apigenin in in vitro Models of Neuroinflammation Associated With Alzheimer's …
NS Dourado, CS Souza, MMA De Almeida… - Frontiers in Aging …, 2020 - frontiersin.org
Neurodegenerative disorders (ND) are characterized by the progressive and irreversible
loss of neurons. Alzheimer's Disease (AD) is the most incident age-related ND, in which the …
loss of neurons. Alzheimer's Disease (AD) is the most incident age-related ND, in which the …
[PDF][PDF] Potential therapeutic use of plant flavonoids in AD and PD
S Meng-Zhen, L Ju, Z Lan-Chun, D Cai-Feng… - Heliyon, 2022 - cell.com
Background Millions of people suffer from Alzheimer's disease (AD) and Parkinson's
disease (PD) worldwide. Due to their complex pathology, no effective pharmacological …
disease (PD) worldwide. Due to their complex pathology, no effective pharmacological …
Effects of polyphenols in aging and neurodegeneration associated with oxidative stress
F Rivas, C Poblete-Aro, ME Pando… - Current Medicinal …, 2022 - ingentaconnect.com
Aging is defined as the functional loss of tissues and organs over time. This is a biological,
irreversible, progressive, and universal process that results from genetic and environmental …
irreversible, progressive, and universal process that results from genetic and environmental …
Neuroprotective, anti-amyloidogenic and neurotrophic effects of apigenin in an Alzheimer's disease mouse model
L Zhao, JL Wang, R Liu, XX Li, JF Li, L Zhang - Molecules, 2013 - mdpi.com
Alzheimer's disease (AD) is a neurodegenerative disorder characterized by extracellular
senile plaques and intracellular neurofibrillary tangles in the brain. Amyloid-β peptides (Aβ) …
senile plaques and intracellular neurofibrillary tangles in the brain. Amyloid-β peptides (Aβ) …