Lipid metabolism, exercise and insulin action

A Bonen, GL Dohm, LJC van Loon - Essays in biochemistry, 2006 - portlandpress.com
Skeletal muscle constitutes 40% of body mass and takes up 80% of a glucose load.
Therefore, impaired glucose removal from the circulation, such as that which occurs in …

Training Induced Changes in the Fatty Acid Composition of Skeletal Muscle Lipids: Functional Aspects

B Vessby, A Andersson, A Sjödin - Skeletal Muscle Metabolism in Exercise …, 1998 - Springer
Insulin sensitivity relates to the fatty acid composition of the skeletal muscle phos-pholipids
and the intramuscular triglyceride content. The fatty acid composition of the phospholipids …

Fast elevation of the intramyocellular lipid content in the presence of circulating free fatty acids and hyperinsulinemia: A dynamic 1H‐MRS study

K Brechtel, DB Dahl, J Machann… - … in Medicine: An …, 2001 - Wiley Online Library
The influence of a short‐term elevation of free fatty acids (FFAs) on intramyocellular lipids
(IMCL) under hyperinsulinemic conditions was monitored in five healthy male subjects in the …

Intramyocellular lipids and their dynamics assessed by 1H magnetic resonance spectroscopy

J Popadic Gacesa, F Schick… - Clinical physiology …, 2017 - Wiley Online Library
This report provides an overview on the present knowledge on intramyocellular lipids (IMCL)
and their dynamics in the course of interventions with physical activity of variable type and …

[HTML][HTML] HSL and ATGL: The movers and shakers of muscle lipolysis

CS Shaw, JA Clark, SO Shepherd - The Journal of Physiology, 2013 - ncbi.nlm.nih.gov
Intramuscular triglyceride(IMTG) accounts for only a fraction of the total lipid store in the
human body. However, given its significant contribution as a substrate for ATP synthesis …

[PDF][PDF] Obesity, hypertension, and insulin resistance

ZT Bloomgarden - Diabetes Care, 2002 - researchgate.net
At a symposium addressing the relationships between obesity, hypertension, and
cardiovascular disease at the ASH, Roger Unger (Dallas, TX) discussed lipotoxicity and the …

Intramuscular lipid metabolism, insulin action, and obesity

LA Consitt, JA Bell, JA Houmard - IUBMB life, 2009 - Wiley Online Library
With the increasing prevalence of obesity, research has focused on the molecular
mechanism (s) linking obesity and skeletal muscle insulin resistance. Metabolic alterations …

Fat as a fuel: emerging understanding of the adipose tissue–skeletal muscle axis

KN Frayn - Acta physiologica, 2010 - Wiley Online Library
The early pioneers in the field of metabolism during exercise such as Lindhard and Krogh
understood the importance of fat as a fuel for muscle contraction. But they could not have …

Intramuscular triglyceride content is increased in IDDM

P Ebeling, B Essen-Gustavsson, JA Tuominen… - Diabetologia, 1998 - Springer
Increased lipid oxidation is related to insulin resistance. Some of the enhanced lipid
utilization may be derived from intramuscular sources. We studied muscle triglyceride (mTG) …

[PDF][PDF] The Relation between Non-adipose Muscle Fat and Hepatic Steatosis Studied with Localized 1H Magnetic Resonance Spectroscopy (1H MRS) and LCMS …

VJT van Ginneken, R Booms, E Verheij, E De Vries… - Anat Physiol, 2016 - academia.edu
Aim/objective: In this study we investigated ectopic fat storage in the muscle and the liver
using 1H Magnetic Resonance Spectroscopy (1H-MRS). The inability to store fat in adipose …