[HTML][HTML] The efficacy and toxicity of gefitinib in treating non-small cell lung cancer: a meta-analysis of 19 randomized clinical trials

H Wo, J He, Y Zhao, H Yu, F Chen, H Yi - Journal of Cancer, 2018 - ncbi.nlm.nih.gov
Background: This meta-analysis evaluated the efficacy and toxicity of gefitinib with other
commonly used drugs in different treatment settings and epidermal growth factor receptor …

Gefitinib vs. chemotherapy as first-line therapy in advanced non-small cell lung cancer: meta-analysis of phase III trials

GY Ku, BA Haaland, G de Lima Lopes Jr - Lung Cancer, 2011 - Elsevier
BACKGROUND: Gefitinib is an oral tyrosine kinase inhibitor against the epidermal growth
factor receptor (EGFR). It has been shown to be active in patients with advanced non-small …

Comparison of gefitinib plus chemotherapy versus gefitinib alone for advanced non-small-cell lung cancer: A meta analysis

M Yi, T He, K Wang, Y Wei - Clinics, 2023 - SciELO Brasil
This study aimed to perform a meta-analysis comparing the efficacy and safety of gefitinib in
combination with chemotherapy versus gefitinib alone in patients with advanced Non-Small …

Gefitinib for the treatment of non-small-cell lung cancer

T Hida, S Ogawa, JC Park, JY Park… - Expert review of …, 2009 - Taylor & Francis
Gefitinib is an orally bioavailable, EGF receptor tyrosine kinase inhibitor and was the first
targeted drug to be approved for non-small-cell lung cancer (NSCLC). Identification of …

Gefitinib for non-small-cell lung cancer treatment

A D'Incecco, F Cappuzzo - Expert opinion on drug safety, 2011 - Taylor & Francis
Introduction: Gefitinib is an EGFR tyrosine kinase inhibitor (EGFR-TKI) that demonstrated
efficacy in patients with advanced non-small cell lung cancer (NSCLC) across therapy lines …

Gefitinib provides similar effectiveness and improved safety than erlotinib for advanced non-small cell lung cancer: A meta-analysis

W Zhang, Y Wei, D Yu, J Xu, J Peng - Medicine, 2018 - journals.lww.com
Background: The epidermal growth factor receptor tyrosine kinase inhibitors gefitinib and
erlotinib are effective for advanced non-small cell lung cancer (NSCLC). This meta-analysis …

Gefitinib compared with systemic chemotherapy as first-line treatment for chemotherapy-naive patients with advanced non-small cell lung cancer: a meta-analysis of …

F Wang, LD Wang, B Li, ZX Sheng - Clinical Oncology, 2012 - Elsevier
To define the efficacy of gefitinib in chemotherapy-naive patients with advanced non-small
cell lung cancer, we carried out a meta-analysis of randomised controlled trials. Medline …

Chemotherapy with or without gefitinib in patients with advanced non-small-cell lung cancer: a meta-analysis of 6844 patients

Z Hang, Z Chao, LY Wang, XIE Hua, Z Jin… - Chinese medical …, 2013 - journals.lww.com
Background Gefitinib is widely used in patients with advanced non-small-cell lung cancer
(NSCLC), in whom chemotherapy had failed. Previous trials reported inconsistent findings …

[HTML][HTML] Multicenter phase II trial of gefitinib first-line therapy followed by chemotherapy in advanced non-small-cell lung cancer (NSCLC): SAKK protocol 19/03

G D'Addario, D Rauch, R Stupp, M Pless, R Stahel… - Annals of oncology, 2008 - Elsevier
Background Gefitinib is active in patients with pretreated non-small-cell lung cancer
(NSCLC). We evaluated the activity and toxicity of gefitinib first-line treatment in advanced …

Frontline gefitinib in advanced non-small cell lung cancer: meta-analysis of published randomized trials

EM Ibrahim - Annals of thoracic medicine, 2010 - journals.lww.com
OBJECTIVE: Gefitinib, a small molecule tyrosine kinase inhibitor, showed a substantial effect
as a salvage treatment for patients with advanced non-small cell lung cancer (NSCLC) who …