Putative staphylococcal enterotoxin possesses two common structural motifs for MHC-II binding
Staphylococcus aureus has become a significant cause of health risks in humankind.
Staphylococcal superantigens (SAgs) or enterotoxins are the key virulent factors that can …
Staphylococcal superantigens (SAgs) or enterotoxins are the key virulent factors that can …
Structure of staphylococcal enterotoxin N: Implications for binding properties to its cellular proteins
C Zeng, Z Liu, Z Han - International Journal of Molecular Sciences, 2019 - mdpi.com
Staphylococcus aureus strains produce a unique family of immunostimulatory exotoxins
termed as bacterial superantigens (SAgs), which cross-link major histocompatibility complex …
termed as bacterial superantigens (SAgs), which cross-link major histocompatibility complex …
Superantigen natural affinity maturation revealed by the crystal structure of staphylococcal enterotoxin G and its binding to T‐cell receptor Vβ8. 2
MM Fernández, S Bhattacharya… - PROTEINS …, 2007 - Wiley Online Library
The illnesses associated with bacterial superantigens (SAgs) such as food poisoning and
toxic shock syndrome, as well as the emerging threat of purpura fulminans and community …
toxic shock syndrome, as well as the emerging threat of purpura fulminans and community …
Staphylococcal enterotoxin H displays unique MHC class II-binding properties
H Nilsson, P Björk, M Dohlsten… - The Journal of …, 1999 - journals.aai.org
Staphylococcal enterotoxin H (SEH) has been described as a superantigen by sequence
homology with the SEA subfamily and briefly characterized for its in vivo activity. In this …
homology with the SEA subfamily and briefly characterized for its in vivo activity. In this …
[HTML][HTML] MHC class II activation and interferon-γ mediate the inhibition of neutrophils and eosinophils by staphylococcal enterotoxin type A (SEA)
AP Ferreira-Duarte, AS Pinheiro-Torres… - Frontiers in cellular …, 2017 - frontiersin.org
Staphylococcal enterotoxins are classified as superantigens that act by linking T-cell
receptor with MHC class II molecules, which are expressed on classical antigen-presenting …
receptor with MHC class II molecules, which are expressed on classical antigen-presenting …
Genome scale analysis of the role of superantigens in Staphylococcus aureus disease pathogenesis
GJC Wilson - 2011 - era.ed.ac.uk
Staphylococcus aureus produces a family of at least 21 distinct superantigens (SAgs) which
include staphylococcal enterotoxins (SEs), staphylococcal enterotoxin-like toxins (SEls), and …
include staphylococcal enterotoxins (SEs), staphylococcal enterotoxin-like toxins (SEls), and …
Identification, cloning and characterization of SpEX exotoxin produced by Staphylococcus pseudintermedius
Staphylococci have evolved numerous strategies to evade their hosts' immune systems.
Some staphylococcal toxins target essential components of host innate immunity, one of the …
Some staphylococcal toxins target essential components of host innate immunity, one of the …
Activation of MyD88 signaling upon staphylococcal enterotoxin binding to MHC class II molecules
TL Kissner, G Ruthel, S Alam, RG Ulrich, S Fernandez… - PloS one, 2011 - journals.plos.org
Ligands binding to Toll-like receptor (TLR), interleukin 1 receptor (IL-1R), or IFN-γR1 are
known to trigger MyD88-mediated signaling, which activates pro-inflammatory cytokine …
known to trigger MyD88-mediated signaling, which activates pro-inflammatory cytokine …
Structural basis for the neutralization and specificity of Staphylococcal enterotoxin B against its MHC Class II binding site
Staphylococcal enterotoxin (SE) B is among the potent toxins produced by Staphylococcus
aureus that cause toxic shock syndrome (TSS), which can result in multi-organ failure and …
aureus that cause toxic shock syndrome (TSS), which can result in multi-organ failure and …
Molecular Characteristics and Pathogenicity of Staphylococcus aureus Exotoxins
Z Zhu, Z Hu, S Li, R Fang, HK Ono, DL Hu - International Journal of …, 2023 - mdpi.com
Staphylococcus aureus stands as one of the most pervasive pathogens given its morbidity
and mortality worldwide due to its roles as an infectious agent that causes a wide variety of …
and mortality worldwide due to its roles as an infectious agent that causes a wide variety of …