SARS-CoV-2 Omicron: evasion of potent humoral responses and resistance to clinical immunotherapeutics relative to viral variants of concern

A Aggarwal, AO Stella, G Walker, A Akerman… - medrxiv, 2021 - medrxiv.org
Genetically distinct viral variants of severe acute respiratory syndrome coronavirus 2 (SARS-
CoV-2) have been recorded since January 2020. Over this time global vaccine programs …

Vaccination-infection interval determines cross-neutralization potency to SARS-CoV-2 Omicron after breakthrough infection by other variants

S Miyamoto, T Arashiro, Y Adachi, S Moriyama… - Med, 2022 - cell.com
Background The immune profile against severe acute respiratory syndrome coronavirus 2
(SARS-CoV-2) has dramatically diversified due to a complex combination of exposure to …

Increased resistance of SARS-CoV-2 Omicron variant to neutralization by vaccine-elicited and therapeutic antibodies

T Tada, H Zhou, BM Dcosta, MI Samanovic… - …, 2022 - thelancet.com
Background SARS-CoV-2 vaccines currently authorized for emergency use have been
highly successful in preventing infection and lessening disease severity. The vaccines …

Considerable escape of SARS-CoV-2 variant Omicron to antibody neutralization

D Planas, N Saunders, P Maes, F Guivel-Benhassine… - BioRxiv, 2021 - biorxiv.org
The SARS-CoV-2 Omicron variant was first identified in November 2021 in Botswana and
South Africa,. It has in the meantime spread to many countries and is expected to rapidly …

SARS-CoV-2 Omicron BA. 5: Evolving tropism and evasion of potent humoral responses and resistance to clinical immunotherapeutics relative to viral variants of …

A Aggarwal, A Akerman, V Milogiannakis, MR Silva… - …, 2022 - thelancet.com
Background Genetically distinct viral variants of severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2) have been recorded since January 2020. The introduction of …

Enhanced antibody responses in fully vaccinated individuals against pan-SARS-CoV-2 variants following Omicron breakthrough infection

HW Jeong, SM Kim, MK Jung, JY Noh, JS Yoo… - Cell Reports …, 2022 - cell.com
Omicron has become the globally dominant severe acute respiratory syndrome coronavirus
2 (SARS-CoV-2) variant, creating additional challenges due to its ability to evade …

Systematical assessment of the impact of single spike mutations of SARS-CoV-2 Omicron sub-variants on the neutralization capacity of post-vaccination sera

M Katzmarzyk, DC Clesle, J van den Heuvel… - Frontiers in …, 2023 - frontiersin.org
Introduction The evolution of novel SARS-CoV-2 variants significantly affects vaccine
effectiveness. While these effects can only be studied retrospectively, neutralizing antibody …

SARS-CoV-2 variant Omicron: currently the most complete “escapee” from neutralization by antibodies and vaccines

M Li, F Lou, H Fan - Signal Transduction and Targeted Therapy, 2022 - nature.com
On December 23, 2021, five groups published their research results of clinical-approved
monoclonal antibodies, convalescent serum, and vaccine serum against B. 1.1. 529 …

Neutralisation sensitivity of the SARS-CoV-2 omicron (B. 1.1. 529) variant: a cross-sectional study

DJ Sheward, C Kim, RA Ehling, A Pankow… - The Lancet Infectious …, 2022 - thelancet.com
Summary Background The SARS-CoV-2 omicron (B. 1.1. 529) variant, which was first
identified in November, 2021, spread rapidly in many countries, with a spike protein highly …

Improved neutralisation of the SARS-CoV-2 Omicron variant following a booster dose of Pfizer-BioNTech (BNT162b2) COVID-19 vaccine

K Basile, RJ Rockett, K McPhie, M Fennell… - Viruses, 2022 - mdpi.com
In late November 2021, the World Health Organization declared the SARS-CoV-2 lineage B.
1.1. 529 the fifth variant of concern, Omicron. This variant has acquired over 30 mutations in …